Who are Tacrolimus capsule's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Elidel, Prograf, Sandimmune, Sandimmune, CYCLOSPORINE, immediate-release tacrolimus.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Tacrolimus capsule — Competitive Intelligence Brief

Tacrolimus capsule (Tacrolimus capsule) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Calcineurin inhibitor. Area: Immunology.

marketed Calcineurin inhibitor Calcineurin (via FKBP12 binding) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Tacrolimus capsule (Tacrolimus capsule) — Oslo University Hospital. Tacrolimus inhibits calcineurin phosphatase, blocking T-cell activation and proliferation by preventing transcription of IL-2 and other cytokine genes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Tacrolimus capsule TARGET	Tacrolimus capsule	Oslo University Hospital	marketed	Calcineurin inhibitor	Calcineurin (via FKBP12 binding)
Elidel	PIMECROLIMUS	Bausch Health	marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	Peptidyl-prolyl cis-trans isomerase FKBP1A	2001-01-01
Prograf	TACROLIMUS	Astellas Pharma	marketed	Calcineurin Inhibitor Immunosuppressant	Interferon gamma	1994-01-01
Sandimmune	cyclosporine	Novartis AG (originally Sandoz)	marketed	Calcineurin inhibitor (immunosuppressant)	Calcineurin subunit B type 1, Canalicular multispecific organic anion transporter 1, Canalicular multispecific organic anion transporter 2	1983-11-14
Sandimmune	Ciclosporin	Novartis	marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	1983-01-01
CYCLOSPORINE	CYCLOSPORINE		marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	calcineurin	1983-01-01
immediate-release tacrolimus	immediate-release tacrolimus	University of Minnesota	marketed	Calcineurin inhibitor	Calcineurin (serine/threonine phosphatase)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2027-11-03 — Sandimmune · 8298568 · Formulation · US
2027-11-03 — Sandimmune · 8298568 · US
2028-05-30 — Prograf · 9549918 · Formulation · US
2028-05-30 — Prograf · 10166190 · Formulation · US
2028-05-30 — Prograf · 11419823 · Formulation · US
2028-05-30 — Prograf · 12403095 · Formulation · US
2028-05-30 — Prograf · 11123331 · Method of Use · US
2028-05-30 — Prograf · 11110081 · Method of Use · US
2028-05-30 — Prograf · 12083103 · Method of Use · US
2028-05-30 — Prograf · 10864199 · Method of Use · US
2028-08-30 — Prograf · 8664239 · Method of Use · US
2028-08-30 — Prograf · 8685998 · Formulation · US
2029-06-02 — Sandimmune · 9132071 · US
2029-06-02 — Sandimmune · 9132071 · Formulation · US
2030-12-13 — Sandimmune · 8614178 · US
2030-12-13 — Sandimmune · 8614178 · Formulation · US
2031-02-25 — Sandimmune · 8292129 · Formulation · US
2031-02-25 — Sandimmune · 8292129 · US
2032-04-16 — Sandimmune · 8561859 · US
2032-04-16 — Sandimmune · 8561859 · Formulation · US
2033-08-23 — Sandimmune · 9937225 · US
2033-08-23 — Sandimmune · 8980839 · US
2033-08-23 — Sandimmune · 10441630 · US
2033-08-23 — Sandimmune · 8980839 · Formulation · US
2033-08-23 — Sandimmune · 9937225 · Formulation · US
2033-08-23 — Sandimmune · 10441630 · Formulation · US
2034-02-07 — Sandimmune · 9676525 · US
2034-02-07 — Sandimmune · 9676525 · Formulation · US
2034-05-11 — Sandimmune · 9669974 · Formulation · US
2034-05-11 — Sandimmune · 9669974 · US

Sponsor landscape (Calcineurin inhibitor class)

Novartis · 4 drugs in this class
Astellas Pharma Inc · 4 drugs in this class
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. · 4 drugs in this class
University of Cincinnati · 3 drugs in this class
Allergan · 3 drugs in this class
Astellas Pharma China, Inc. · 3 drugs in this class
Novaliq GmbH · 3 drugs in this class
Hoffmann-La Roche · 3 drugs in this class
LEO Pharma · 3 drugs in this class
Santen SAS · 3 drugs in this class

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Cite this brief

Drug Landscape (2026). Tacrolimus capsule — Competitive Intelligence Brief. https://druglandscape.com/ci/tacrolimus-capsule. Accessed 2026-05-14.

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