Who are Prograf's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Gamifant, Interferon Gamma 1-b, Elidel, Sandimmune, CYCLOSPORINE.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Prograf — Competitive Intelligence Brief

Prograf (TACROLIMUS) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Calcineurin Inhibitor Immunosuppressant. Area: Immunology.

marketed Calcineurin Inhibitor Immunosuppressant Interferon gamma Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Prograf (TACROLIMUS) — Astellas Pharma. Prograf works by inhibiting the activation of T-lymphocytes, a type of immune cell.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Prograf TARGET	TACROLIMUS	Astellas Pharma	marketed	Calcineurin Inhibitor Immunosuppressant	Interferon gamma	1994-01-01
Gamifant	EMAPALUMAB	Novimmune S.A.	marketed	Interferon gamma Blocker [EPC]	Interferon gamma	2018-01-01
Interferon Gamma 1-b	Interferon Gamma 1-b	Assistance Publique - Hôpitaux de Paris	phase 3	Cytokine / Immunomodulator	Interferon gamma receptor (IFNGR)
Elidel	PIMECROLIMUS	Bausch Health	marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	Peptidyl-prolyl cis-trans isomerase FKBP1A	2001-01-01
Sandimmune	Ciclosporin	Novartis	marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	1983-01-01
CYCLOSPORINE	CYCLOSPORINE		marketed	Calcineurin Inhibitor Immunosuppressant [EPC]	calcineurin	1983-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2027-11-03 — Sandimmune · 8298568 · US
2028-05-30 — Prograf · 11123331 · Method of Use · US
2028-05-30 — Prograf · 12403095 · Formulation · US
2028-05-30 — Prograf · 9549918 · Formulation · US
2028-05-30 — Prograf · 11419823 · Formulation · US
2028-05-30 — Prograf · 10166190 · Formulation · US
2028-05-30 — Prograf · 10864199 · Method of Use · US
2028-05-30 — Prograf · 11110081 · Method of Use · US
2028-05-30 — Prograf · 12083103 · Method of Use · US
2028-08-30 — Prograf · 8685998 · Formulation · US
2028-08-30 — Prograf · 8664239 · Method of Use · US
2029-06-02 — Sandimmune · 9132071 · US
2030-12-13 — Sandimmune · 8614178 · US
2031-02-25 — Sandimmune · 8292129 · US
2032-04-16 — Sandimmune · 8561859 · US
2033-08-23 — Sandimmune · 10441630 · US
2033-08-23 — Sandimmune · 9937225 · US
2033-08-23 — Sandimmune · 8980839 · US
2034-02-07 — Sandimmune · 9676525 · US
2034-05-11 — Sandimmune · 9669974 · US
2037-02-28 — Sandimmune · 10918694 · US
2037-09-22 — Sandimmune · 10813976 · US
2038-11-20 — Sandimmune · 11154513 · US
2039-10-11 — Sandimmune · 11413323 · US

Sponsor landscape (Calcineurin Inhibitor Immunosuppressant class)

Astellas Pharma · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Prograf — Competitive Intelligence Brief. https://druglandscape.com/ci/tacrolimus. Accessed 2026-05-13.

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