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Switch to TDF/FTC/RPV after 24 weeks — Competitive Intelligence Brief
marketed
Antiretroviral combination therapy (NRTI + NNRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Switch to TDF/FTC/RPV after 24 weeks (Switch to TDF/FTC/RPV after 24 weeks) — Azienda Ospedaliera San Gerardo di Monza. A combination antiretroviral regimen that suppresses HIV replication by inhibiting reverse transcriptase and integrase through three complementary agents.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Switch to TDF/FTC/RPV after 24 weeks TARGET | Switch to TDF/FTC/RPV after 24 weeks | Azienda Ospedaliera San Gerardo di Monza | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| 3TC | 3TC | Avexa | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase; hepatitis B polymerase | |
| Lamivudine (LAM) | Lamivudine (LAM) | Hoffmann-La Roche | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase; Hepatitis B virus reverse transcriptase | |
| tenofovir disproxil fumarate/emtricitabine | tenofovir disproxil fumarate/emtricitabine | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor combination | HIV reverse transcriptase | |
| Lamiduvine (Epivir) | Lamiduvine (Epivir) | Catholic University of the Sacred Heart | marketed | Nucleoside Reverse Transcriptase Inhibitor (NRTI) | HIV reverse transcriptase | |
| Truvada Pill | Truvada Pill | University of North Carolina, Chapel Hill | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| Doravirine + tenofovir DF + lamivudine | Doravirine + tenofovir DF + lamivudine | Instituto Mexicano del Seguro Social | marketed | Antiretroviral combination (NNRTI + NRTIs) | HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NRTI + NNRTI) class)
- GlaxoSmithKline · 2 drugs in this class
- Clinical Trial Agency of HIV Study Group · 1 drug in this class
- Hospital Clinic of Barcelona · 1 drug in this class
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · 1 drug in this class
- National Center for AIDS/STD Control and Prevention, China CDC · 1 drug in this class
- Peking Union Medical College Hospital · 1 drug in this class
- Sheba Medical Center · 1 drug in this class
- Azienda Ospedaliera San Gerardo di Monza · 1 drug in this class
- University of KwaZulu · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Switch to TDF/FTC/RPV after 24 weeks — Competitive Intelligence Brief. https://druglandscape.com/ci/switch-to-tdf-ftc-rpv-after-24-weeks. Accessed 2026-05-16.
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