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Switch ritonavir-boosted PI — Competitive Intelligence Brief
marketed
Protease inhibitor (boosted)
HIV protease
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Switch ritonavir-boosted PI (Switch ritonavir-boosted PI) — Juan A. Arnaiz. A ritonavir-boosted protease inhibitor combination that inhibits HIV protease to prevent viral replication and reduce viral load.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Switch ritonavir-boosted PI TARGET | Switch ritonavir-boosted PI | Juan A. Arnaiz | marketed | Protease inhibitor (boosted) | HIV protease | |
| LPV/r | LPV/r | The HIV Netherlands Australia Thailand Research Collaboration | marketed | Protease inhibitor (PI) combination | HIV protease | |
| HIV therapy | HIV therapy | ViiV Healthcare | marketed | Antiretroviral agents (multiple classes: NRTIs, NNRTIs, PIs, INSTIs, entry inhibitors) | Multiple targets depending on specific agent (HIV reverse transcriptase, HIV protease, HIV integrase, CCR5 co-receptor, gp120/gp41 envelope proteins) | |
| Combivir+Kaletra | Combivir+Kaletra | Hospital Clinic of Barcelona | marketed | Antiretroviral combination therapy (NRTI + protease inhibitor) | HIV reverse transcriptase and HIV protease | |
| lopinavir with ritonavir in 1:1 ratio | lopinavir with ritonavir in 1:1 ratio | Drugs for Neglected Diseases | marketed | HIV protease inhibitor | HIV protease | |
| LPV/r + TDF/FTC or TDF/3TC | LPV/r + TDF/FTC or TDF/3TC | The HIV Netherlands Australia Thailand Research Collaboration | marketed | Antiretroviral combination therapy (protease inhibitor + nucleoside reverse transcriptase inhibitors) | HIV protease; HIV reverse transcriptase | |
| Fosamprenavir/ritonavir | Fosamprenavir/ritonavir | ViiV Healthcare | marketed | HIV protease inhibitor | HIV protease |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Protease inhibitor (boosted) class)
- Community Research Initiative of New England · 1 drug in this class
- Juan A. Arnaiz · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Switch ritonavir-boosted PI — Competitive Intelligence Brief. https://druglandscape.com/ci/switch-ritonavir-boosted-pi. Accessed 2026-05-16.
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