Who are Surgery with Naproxen and Esomeprazole's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Diclofenac + Omeprazole, Ketoprofen and Omeprazole, FDC KETOPROFEN+OMEPRAZOLE, Nimesulide + Pantoprazole.

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Last reviewed 2026-05-18 · How we verify

Surgery with Naproxen and Esomeprazole — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Surgery with Naproxen and Esomeprazole (Surgery with Naproxen and Esomeprazole) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NSAID + Proton pump inhibitor combination. Area: Pain management / Gastroenterology.

marketed NSAID + Proton pump inhibitor combination COX-1/COX-2 (naproxen); H+/K+-ATPase (esomeprazole) Pain management / Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Surgery with Naproxen and Esomeprazole (Surgery with Naproxen and Esomeprazole) — Giovana Maria Weckwerth. Naproxen reduces post-surgical pain and inflammation via COX inhibition, while esomeprazole protects the gastrointestinal tract by suppressing gastric acid production.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Surgery with Naproxen and Esomeprazole TARGET	Surgery with Naproxen and Esomeprazole	Giovana Maria Weckwerth	marketed	NSAID + Proton pump inhibitor combination	COX-1/COX-2 (naproxen); H+/K+-ATPase (esomeprazole)
Diclofenac + Omeprazole	Diclofenac + Omeprazole	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	marketed	NSAID + Proton pump inhibitor combination	COX-1/COX-2 (diclofenac); H+/K+-ATPase (omeprazole)
Ketoprofen and Omeprazole	Ketoprofen and Omeprazole	Luis Fernando Simoneti	marketed	NSAID + Proton pump inhibitor combination	COX-1/COX-2 (ketoprofen); H+/K+-ATPase (omeprazole)
FDC KETOPROFEN+OMEPRAZOLE	FDC KETOPROFEN+OMEPRAZOLE	Sanofi	phase 3	NSAID + Proton pump inhibitor combination	COX-1/COX-2 (ketoprofen); H+/K+-ATPase (omeprazole)
Nimesulide + Pantoprazole	Nimesulide + Pantoprazole	EMS	phase 3	NSAID + Proton pump inhibitor combination	COX-2 enzyme (nimesulide); H+/K+-ATPase (pantoprazole)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NSAID + Proton pump inhibitor combination class)

EMS · 1 drug in this class
Giovana Maria Weckwerth · 1 drug in this class
Luis Fernando Simoneti · 1 drug in this class
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · 1 drug in this class
Sanofi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Surgery with Naproxen and Esomeprazole — Competitive Intelligence Brief. https://druglandscape.com/ci/surgery-with-naproxen-and-esomeprazole. Accessed 2026-05-18.

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