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Stopping dupilumab — Competitive Intelligence Brief
marketed
Monoclonal antibody
Interleukin-4 receptor alpha subunit (IL-4Rα)
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Stopping dupilumab (Stopping dupilumab) — University Hospital, Toulouse. Dupilumab is a human monoclonal antibody that binds to the interleukin-4 receptor alpha subunit, blocking the signaling of IL-4 and IL-13, which are key cytokines in type 2 inflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Stopping dupilumab TARGET | Stopping dupilumab | University Hospital, Toulouse | marketed | Monoclonal antibody | Interleukin-4 receptor alpha subunit (IL-4Rα) | |
| [89Zr]Zr-crefmirlimab berdoxam | 89zr-zr-crefmirlimab-berdoxam | Pfizer | marketed | Radiolabeled Monoclonal Antibody | Fibroblast Activation Protein (FAP) | Not specified |
| Venetoclax; Rituximab | venetoclax-rituximab | Pfizer | marketed | BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) | BCL-2 (venetoclax); CD20 (rituximab) | N/A |
| Hympavzi | MARSTACIMAB | Pfizer Inc | marketed | Monoclonal Antibody | Factor Xa | 2025-01-01 |
| Beyfortus | NIRSEVIMAB | AstraZeneca | marketed | Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] | RSV | 2023-01-01 |
| Darzalex | daratumumab | Johnson & Johnson | marketed | Monoclonal antibody | CD38 | 2015-01-01 |
| Praxbind | IDARUCIZUMAB | Boehringer Ingelheim | marketed | Humanized Monoclonal Antibody Fragment [EPC] | dabigatran and its acylglucuronide metabolites | 2015-01-01 |
Recent regulatory actions (last 90 days)
- — Beyfortus · FDA · approved · US · AstraZeneca
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody class)
- Pfizer · 7 drugs in this class
- argenx · 7 drugs in this class
- Johnson & Johnson · 2 drugs in this class
- German CLL Study Group · 2 drugs in this class
- Amgen · 2 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- Brii Biosciences Limited · 2 drugs in this class
- Alexion Pharmaceuticals, Inc. · 2 drugs in this class
- Biotest · 2 drugs in this class
- Fondazione Italiana Linfomi - ETS · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Stopping dupilumab — Competitive Intelligence Brief. https://druglandscape.com/ci/stopping-dupilumab. Accessed 2026-05-16.
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