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Statins with or without ezetimibe — Competitive Intelligence Brief
phase 3
HMG-CoA reductase inhibitor
HMG-CoA reductase
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Statins with or without ezetimibe (Statins with or without ezetimibe) — Beijing Anzhen Hospital. Statins inhibit HMG-CoA reductase, a key enzyme in cholesterol biosynthesis, while ezetimibe inhibits the absorption of cholesterol in the small intestine.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Statins with or without ezetimibe TARGET | Statins with or without ezetimibe | Beijing Anzhen Hospital | phase 3 | HMG-CoA reductase inhibitor | HMG-CoA reductase | |
| Crestor | rosuvastatin | AstraZeneca | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase | 2003-01-01 |
| Lipitor | atorvastatin | Pfizer Inc. | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase | 1996-12-17 |
| Lescol | FLUVASTATIN | Novartis | marketed | HMG-CoA Reductase Inhibitor | HMG-CoA reductase | 1993-01-01 |
| FLUVASTATIN SODIUM | FLUVASTATIN SODIUM | marketed | HMG-CoA reductase | 1993-01-01 | ||
| HMG CoA inhibitor | HMG CoA inhibitor | AstraZeneca | marketed | Statin (HMG-CoA reductase inhibitor) | HMG-CoA reductase | |
| Statin (simvastatin) | Statin (simvastatin) | University of Aarhus | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HMG-CoA reductase inhibitor class)
- Beijing Anzhen Hospital · 1 drug in this class
- Boryung Pharmaceutical Co., Ltd · 1 drug in this class
- Jeil Pharmaceutical Co., Ltd. · 1 drug in this class
- National Heart, Lung, and Blood Institute (NHLBI) · 1 drug in this class
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- Statins with or without ezetimibe CI watch — RSS
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- Statins with or without ezetimibe alone — RSS
- Whole HMG-CoA reductase inhibitor class — RSS
Cite this brief
Drug Landscape (2026). Statins with or without ezetimibe — Competitive Intelligence Brief. https://druglandscape.com/ci/statins-with-or-without-ezetimibe. Accessed 2026-05-15.
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