Who are Statins, HMG CoA's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Crestor, Lipitor, Lescol, FLUVASTATIN SODIUM, Omega 3-Atorvastatin, atorvastatin and clopidogrel.

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Last reviewed 2026-06-10 · How we verify

Statins, HMG CoA — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Statins, HMG CoA (Statins, HMG CoA) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: HMG-CoA reductase inhibitor. Area: Cardiovascular.

marketed HMG-CoA reductase inhibitor HMG-CoA reductase Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Statins, HMG CoA (Statins, HMG CoA) — National Heart, Lung, and Blood Institute (NHLBI). Statins inhibit HMG-CoA reductase, the enzyme that catalyzes the rate-limiting step in cholesterol synthesis, thereby reducing LDL cholesterol levels.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Statins, HMG CoA TARGET	Statins, HMG CoA	National Heart, Lung, and Blood Institute (NHLBI)	marketed	HMG-CoA reductase inhibitor	HMG-CoA reductase
Crestor	rosuvastatin	AstraZeneca	marketed	HMG-CoA reductase inhibitor (statin)	HMG-CoA reductase	2003-01-01
Lipitor	atorvastatin	Pfizer Inc.	marketed	HMG-CoA reductase inhibitor (statin)	HMG-CoA reductase	1996-12-17
Lescol	FLUVASTATIN	Novartis	marketed	HMG-CoA Reductase Inhibitor	HMG-CoA reductase	1993-01-01
FLUVASTATIN SODIUM	FLUVASTATIN SODIUM		marketed		HMG-CoA reductase	1993-01-01
Omega 3-Atorvastatin	Omega 3-Atorvastatin	Seoul National University Bundang Hospital	marketed	Statin + omega-3 fatty acid combination	HMG-CoA reductase (atorvastatin); GPR120, GPR40 (omega-3 signaling)
atorvastatin and clopidogrel	atorvastatin and clopidogrel	Ospedale Misericordia e Dolce	marketed	Statin and P2Y12 platelet inhibitor combination	HMG-CoA reductase and P2Y12 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2037-06-07 — Lipitor · 11654106 · US
2037-06-07 — Lipitor · 11369567 · US

Sponsor landscape (HMG-CoA reductase inhibitor class)

Beijing Anzhen Hospital · 1 drug in this class
Boryung Pharmaceutical Co., Ltd · 1 drug in this class
Jeil Pharmaceutical Co., Ltd. · 1 drug in this class
National Heart, Lung, and Blood Institute (NHLBI) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Statins, HMG CoA — Competitive Intelligence Brief. https://druglandscape.com/ci/statins-hmg-coa. Accessed 2026-06-10.

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