Last reviewed · How we verify
Standard dose: standard XELOX + sintilimab — Competitive Intelligence Brief
phase 3
Chemotherapy + PD-1 inhibitor combination
PD-1 (sintilimab component); DNA/thymidylate synthase (XELOX component)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Standard dose: standard XELOX + sintilimab (Standard dose: standard XELOX + sintilimab) — Sun Yat-sen University. XELOX chemotherapy combined with sintilimab (a PD-1 inhibitor) works by killing cancer cells through chemotoxicity while simultaneously unleashing immune cells to attack tumors by blocking the PD-1 checkpoint.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Standard dose: standard XELOX + sintilimab TARGET | Standard dose: standard XELOX + sintilimab | Sun Yat-sen University | phase 3 | Chemotherapy + PD-1 inhibitor combination | PD-1 (sintilimab component); DNA/thymidylate synthase (XELOX component) | |
| SOX plus PD-1 inhibitor | SOX plus PD-1 inhibitor | Liaoning Cancer Hospital & Institute | marketed | Chemotherapy + PD-1 inhibitor combination | PD-1 (programmed death receptor 1); S-1 (thymidylate synthase/5-FU metabolism); oxaliplatin (DNA cross-linking) | |
| Chemotherapy+Pembrolizumab. | Chemotherapy+Pembrolizumab. | Tang-Du Hospital | marketed | Chemotherapy + PD-1 inhibitor combination | PD-1 (programmed death receptor 1); chemotherapy targets DNA | |
| TPC combined with Tislelizumab | TPC combined with Tislelizumab | XIANG YANQUN | phase 3 | Chemotherapy + PD-1 inhibitor combination | PD-1 (Tislelizumab component); TPC targets DNA/cell cycle |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy + PD-1 inhibitor combination class)
- Liaoning Cancer Hospital & Institute · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
- Tang-Du Hospital · 1 drug in this class
- XIANG YANQUN · 1 drug in this class
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- Standard dose: standard XELOX + sintilimab CI watch — RSS
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Cite this brief
Drug Landscape (2026). Standard dose: standard XELOX + sintilimab — Competitive Intelligence Brief. https://druglandscape.com/ci/standard-dose-standard-xelox-sintilimab. Accessed 2026-05-17.
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