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Standard: Aprepitant — Competitive Intelligence Brief

Standard: Aprepitant (Standard: Aprepitant) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NK1 receptor antagonist. Area: Oncology.

phase 3 NK1 receptor antagonist NK1 receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Standard: Aprepitant (Standard: Aprepitant) — CCTU. Aprepitant is a substance P/neurokinin 1 (NK1) receptor antagonist.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Standard: Aprepitant TARGET Standard: Aprepitant CCTU phase 3 NK1 receptor antagonist NK1 receptor
Fosaprepitant for Injection Fosaprepitant for Injection Montefiore Medical Center marketed NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor)
fosnetupitant/ palonosetron fosnetupitant/ palonosetron Helsinn Healthcare SA marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (substance P receptor) / 5-HT3 receptor
Ramosetron, Aprepitant, Dexamethasone Ramosetron, Aprepitant, Dexamethasone Hallym University Medical Center marketed 5-HT3 antagonist / NK1 antagonist / corticosteroid combination 5-HT3 receptor, NK1 receptor, glucocorticoid receptor
EMEND EMEND Merck Sharp & Dohme LLC marketed Neurokinin-1 (NK1) receptor antagonist NK1 receptor (neurokinin-1 receptor)
Dexamethasone, Ondansetron, Aprepitant Dexamethasone, Ondansetron, Aprepitant Ottawa Hospital Research Institute marketed Antiemetic combination (corticosteroid + 5-HT3 antagonist + NK1 antagonist) Glucocorticoid receptor, 5-HT3 receptor, NK1 receptor
Aprepitant plus Ondansetron Aprepitant plus Ondansetron University of Pittsburgh marketed NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NK1 receptor antagonist class)

  1. Merck Sharp & Dohme LLC · 4 drugs in this class
  2. GlaxoSmithKline · 3 drugs in this class
  3. Organon and Co · 3 drugs in this class
  4. CCTU · 2 drugs in this class
  5. Acacia Pharma Ltd · 2 drugs in this class
  6. Sanofi · 1 drug in this class
  7. Santen SAS · 1 drug in this class
  8. CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
  9. Montefiore Medical Center · 1 drug in this class
  10. New Mexico Cancer Research Alliance · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Standard: Aprepitant — Competitive Intelligence Brief. https://druglandscape.com/ci/standard-aprepitant. Accessed 2026-05-13.

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