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Standard: Aprepitant — Competitive Intelligence Brief
phase 3
NK1 receptor antagonist
NK1 receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Standard: Aprepitant (Standard: Aprepitant) — CCTU. Aprepitant is a substance P/neurokinin 1 (NK1) receptor antagonist.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Standard: Aprepitant TARGET | Standard: Aprepitant | CCTU | phase 3 | NK1 receptor antagonist | NK1 receptor | |
| Fosaprepitant for Injection | Fosaprepitant for Injection | Montefiore Medical Center | marketed | NK1 receptor antagonist | NK1 receptor (neurokinin-1 receptor) | |
| fosnetupitant/ palonosetron | fosnetupitant/ palonosetron | Helsinn Healthcare SA | marketed | NK1 receptor antagonist / 5-HT3 receptor antagonist combination | NK1 receptor (substance P receptor) / 5-HT3 receptor | |
| Ramosetron, Aprepitant, Dexamethasone | Ramosetron, Aprepitant, Dexamethasone | Hallym University Medical Center | marketed | 5-HT3 antagonist / NK1 antagonist / corticosteroid combination | 5-HT3 receptor, NK1 receptor, glucocorticoid receptor | |
| EMEND | EMEND | Merck Sharp & Dohme LLC | marketed | Neurokinin-1 (NK1) receptor antagonist | NK1 receptor (neurokinin-1 receptor) | |
| Dexamethasone, Ondansetron, Aprepitant | Dexamethasone, Ondansetron, Aprepitant | Ottawa Hospital Research Institute | marketed | Antiemetic combination (corticosteroid + 5-HT3 antagonist + NK1 antagonist) | Glucocorticoid receptor, 5-HT3 receptor, NK1 receptor | |
| Aprepitant plus Ondansetron | Aprepitant plus Ondansetron | University of Pittsburgh | marketed | NK1 receptor antagonist + 5-HT3 receptor antagonist combination | NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NK1 receptor antagonist class)
- Merck Sharp & Dohme LLC · 4 drugs in this class
- GlaxoSmithKline · 3 drugs in this class
- Organon and Co · 3 drugs in this class
- CCTU · 2 drugs in this class
- Acacia Pharma Ltd · 2 drugs in this class
- Sanofi · 1 drug in this class
- Santen SAS · 1 drug in this class
- CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
- Montefiore Medical Center · 1 drug in this class
- New Mexico Cancer Research Alliance · 1 drug in this class
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Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Standard: Aprepitant CI watch — RSS
- Standard: Aprepitant CI watch — Atom
- Standard: Aprepitant CI watch — JSON
- Standard: Aprepitant alone — RSS
- Whole NK1 receptor antagonist class — RSS
Cite this brief
Drug Landscape (2026). Standard: Aprepitant — Competitive Intelligence Brief. https://druglandscape.com/ci/standard-aprepitant. Accessed 2026-05-13.
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