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SPM 962 — Competitive Intelligence Brief
phase 3
S1P receptor modulator
S1PR1
Autoimmune diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
SPM 962 (SPM 962) — Otsuka Pharmaceutical Co., Ltd.. SPM 962 is a selective, high-affinity, and orally bioavailable small molecule inhibitor of the sphingosine-1-phosphate receptor 1 (S1PR1).
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SPM 962 TARGET | SPM 962 | Otsuka Pharmaceutical Co., Ltd. | phase 3 | S1P receptor modulator | S1PR1 | |
| TVP-1012 | TVP-1012 | Takeda | phase 3 | S1P receptor modulator | S1PR1 | |
| Aplause® | Aplause® | Phytopharm Consulting Brazil | phase 3 | S1P receptor modulator | S1PR1 | |
| NPC-16 Continuous Dosing Regimen Group | NPC-16 Continuous Dosing Regimen Group | Nobelpharma | phase 3 | S1P receptor modulator | S1PR1 | |
| OPC-262 | OPC-262 | Kyowa Kirin Co., Ltd. | phase 3 | S1PR1 inhibitor | S1PR1 | |
| SPMC 2 | SPMC 2 | Korea University Anam Hospital | phase 3 | Sphingosine-1-phosphate receptor 1 (S1PR1) modulator | S1PR1 | |
| NPC-16 Standard Dosing Regimen Group | NPC-16 Standard Dosing Regimen Group | Nobelpharma | phase 3 | S1P receptor modulator | S1PR1 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (S1P receptor modulator class)
- Promius Pharma, LLC · 2 drugs in this class
- Nobelpharma · 2 drugs in this class
- Bausch & Lomb Incorporated · 1 drug in this class
- Biogen · 1 drug in this class
- Celgene · 1 drug in this class
- Geropharm · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- Huazhong University of Science and Technology · 1 drug in this class
- Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). SPM 962 — Competitive Intelligence Brief. https://druglandscape.com/ci/spm-962. Accessed 2026-05-13.
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