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SOX plus PD-1 inhibitor — Competitive Intelligence Brief

SOX plus PD-1 inhibitor (SOX plus PD-1 inhibitor) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Chemotherapy + PD-1 inhibitor combination. Area: Oncology.

marketed Chemotherapy + PD-1 inhibitor combination PD-1 (programmed death receptor 1); S-1 (thymidylate synthase/5-FU metabolism); oxaliplatin (DNA cross-linking) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

SOX plus PD-1 inhibitor (SOX plus PD-1 inhibitor) — Liaoning Cancer Hospital & Institute. SOX chemotherapy combined with a PD-1 inhibitor uses cytotoxic drugs to kill cancer cells while simultaneously blocking PD-1 to enhance anti-tumor immune responses.

Comparator set (3 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
SOX plus PD-1 inhibitor TARGET SOX plus PD-1 inhibitor Liaoning Cancer Hospital & Institute marketed Chemotherapy + PD-1 inhibitor combination PD-1 (programmed death receptor 1); S-1 (thymidylate synthase/5-FU metabolism); oxaliplatin (DNA cross-linking)
Chemotherapy+Pembrolizumab. Chemotherapy+Pembrolizumab. Tang-Du Hospital marketed Chemotherapy + PD-1 inhibitor combination PD-1 (programmed death receptor 1); chemotherapy targets DNA
TPC combined with Tislelizumab TPC combined with Tislelizumab XIANG YANQUN phase 3 Chemotherapy + PD-1 inhibitor combination PD-1 (Tislelizumab component); TPC targets DNA/cell cycle
Standard dose: standard XELOX + sintilimab Standard dose: standard XELOX + sintilimab Sun Yat-sen University phase 3 Chemotherapy + PD-1 inhibitor combination PD-1 (sintilimab component); DNA/thymidylate synthase (XELOX component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Chemotherapy + PD-1 inhibitor combination class)

  1. Liaoning Cancer Hospital & Institute · 1 drug in this class
  2. Sun Yat-sen University · 1 drug in this class
  3. Tang-Du Hospital · 1 drug in this class
  4. XIANG YANQUN · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SOX plus PD-1 inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/sox-plus-pd-1-inhibitor. Accessed 2026-05-16.

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