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sodium valproate with Clozapine — Competitive Intelligence Brief
marketed
Antipsychotic + mood stabilizer combination
Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
sodium valproate with Clozapine (sodium valproate with Clozapine) — Shanghai Mental Health Center. This combination pairs sodium valproate (a histone deacetylase inhibitor and GABA enhancer) with clozapine (an atypical antipsychotic) to provide synergistic effects on mood stabilization and antipsychotic activity.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| sodium valproate with Clozapine TARGET | sodium valproate with Clozapine | Shanghai Mental Health Center | marketed | Antipsychotic + mood stabilizer combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antipsychotic + mood stabilizer combination class)
- Shanghai Mental Health Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). sodium valproate with Clozapine — Competitive Intelligence Brief. https://druglandscape.com/ci/sodium-valproate-with-clozapine. Accessed 2026-05-16.
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