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SOC: Soluble guanylate cyclase stimulator — Competitive Intelligence Brief

SOC: Soluble guanylate cyclase stimulator (SOC: Soluble guanylate cyclase stimulator) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Soluble guanylate cyclase stimulator. Area: Cardiovascular.

phase 3 Soluble guanylate cyclase stimulator Soluble guanylate cyclase (sGC) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

SOC: Soluble guanylate cyclase stimulator (SOC: Soluble guanylate cyclase stimulator) — Actelion. Soluble guanylate cyclase stimulators directly activate the enzyme soluble guanylate cyclase to increase intracellular cyclic GMP levels, promoting vasodilation and reducing pulmonary vascular resistance.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
SOC: Soluble guanylate cyclase stimulator TARGET SOC: Soluble guanylate cyclase stimulator Actelion phase 3 Soluble guanylate cyclase stimulator Soluble guanylate cyclase (sGC)
Verquvo VERICIGUAT Merck & Co. marketed Soluble Guanylate Cyclase Stimulator [EPC] Guanylate cyclase soluble subunit beta-1 2021-01-01
Adempas RIOCIGUAT Bayer marketed Soluble Guanylate Cyclase Stimulator [EPC] Guanylate cyclase soluble subunit beta-1 2013-01-01
Riociguat Oral Product Riociguat Oral Product University of Calgary marketed Soluble guanylate cyclase stimulator Soluble guanylate cyclase (sGC)
Riociguat (Adempas) Riociguat (Adempas) Chinese University of Hong Kong marketed Soluble guanylate cyclase stimulator Soluble guanylate cyclase (sGC)
Riociguat Pill Riociguat Pill University of Arizona phase 3 Soluble guanylate cyclase stimulator Soluble guanylate cyclase (sGC)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Soluble guanylate cyclase stimulator class)

  1. Actelion · 1 drug in this class
  2. Chinese University of Hong Kong · 1 drug in this class
  3. University of Arizona · 1 drug in this class
  4. University of Calgary · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SOC: Soluble guanylate cyclase stimulator — Competitive Intelligence Brief. https://druglandscape.com/ci/soc-soluble-guanylate-cyclase-stimulator. Accessed 2026-05-16.

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