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Sitravatinib — Competitive Intelligence Brief
marketed
Tyrosine kinase inhibitor
Tyrosine kinases
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Sitravatinib (sitravatinib) — Pfizer.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Sitravatinib TARGET | sitravatinib | Pfizer | marketed | Tyrosine kinase inhibitor | Tyrosine kinases | |
| Sutent | Sunitinib Malate | Pfizer | marketed | Small molecule kinase inhibitor | Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET | 2006-01-01 |
| Cipterbin Combined With Vinorelbine | Cipterbin Combined With Vinorelbine | Zhejiang Cancer Hospital | marketed | Tyrosine kinase inhibitor combined with vinca alkaloid | Multiple tyrosine kinases (cipterbin); tubulin (vinorelbine) | |
| pirfenidone or nintedanib | pirfenidone or nintedanib | Hospices Civils de Lyon | marketed | Antifibrotic agent | Pirfenidone: TGF-β pathway; Nintedanib: FGFR, VEGFR, PDGFR tyrosine kinases | |
| TT-00420 (tinengotinib) | TT-00420 (tinengotinib) | TransThera Sciences (Nanjing), Inc. | phase 3 | Multi-targeted tyrosine kinase inhibitor | VEGFR, FGFR, and other receptor tyrosine kinases | |
| OTX-TKI | OTX-TKI | Ocular Therapeutix, Inc. | phase 3 | Tyrosine kinase inhibitor | Multiple receptor tyrosine kinases (RTKs) | |
| Lenvatinib plus TACE | Lenvatinib plus TACE | Second Affiliated Hospital of Guangzhou Medical University | phase 3 | Multi-targeted tyrosine kinase inhibitor (in combination with transarterial chemoembolization) | FGFR, VEGFR, RET, KIT, and other receptor tyrosine kinases |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Tyrosine kinase inhibitor class)
- Jiangsu HengRui Medicine Co., Ltd. · 5 drugs in this class
- Centre Leon Berard · 2 drugs in this class
- AB Science · 2 drugs in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- Betta Pharmaceuticals Co., Ltd. · 1 drug in this class
- Angion Biomedica Corp · 1 drug in this class
- Beijing InnoCare Pharma Tech Co., Ltd. · 1 drug in this class
- Chang-Ming Huang, Prof. · 1 drug in this class
- Deciphera Pharmaceuticals, LLC · 1 drug in this class
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Sitravatinib — Competitive Intelligence Brief. https://druglandscape.com/ci/sitravatinib. Accessed 2026-05-13.
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