Who are Sitagliptin phosphate/metformin hydrochloride FDC's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Linagliptin / Metformin Oral Tablet, Saxagliptin-Metformin XR.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-17 · How we verify

Sitagliptin phosphate/metformin hydrochloride FDC — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sitagliptin phosphate/metformin hydrochloride FDC (Sitagliptin phosphate/metformin hydrochloride FDC) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: DPP-4 inhibitor / biguanide combination. Area: Diabetes.

marketed DPP-4 inhibitor / biguanide combination DPP-4 enzyme / metformin (AMPK pathway) Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

Sitagliptin phosphate/metformin hydrochloride FDC (Sitagliptin phosphate/metformin hydrochloride FDC) — Merck Sharp & Dohme LLC. This combination drug inhibits dipeptidyl peptidase-4 (DPP-4) to increase incretin levels while metformin reduces hepatic glucose production and improves insulin sensitivity.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Sitagliptin phosphate/metformin hydrochloride FDC TARGET	Sitagliptin phosphate/metformin hydrochloride FDC	Merck Sharp & Dohme LLC	marketed	DPP-4 inhibitor / biguanide combination	DPP-4 enzyme / metformin (AMPK pathway)
Linagliptin / Metformin Oral Tablet	Linagliptin / Metformin Oral Tablet	Universidad de Guanajuato	marketed	DPP-4 inhibitor / Biguanide combination	DPP-4 (dipeptidyl peptidase-4) / AMPK pathway
Saxagliptin-Metformin XR	Saxagliptin-Metformin XR	Woman's	phase 3	DPP-4 inhibitor / Biguanide combination	DPP-4 enzyme; metformin targets mitochondrial glycerophosphate dehydrogenase and AMPK

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (DPP-4 inhibitor / biguanide combination class)

Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sitagliptin phosphate/metformin hydrochloride FDC — Competitive Intelligence Brief. https://druglandscape.com/ci/sitagliptin-phosphate-metformin-hydrochloride-fdc. Accessed 2026-05-17.

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