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Single Agent IV Antibiotic Therapy - MSSA — Competitive Intelligence Brief
marketed
Beta-lactam antibiotic
Penicillin-binding proteins (PBPs); bacterial cell wall peptidoglycan
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Single Agent IV Antibiotic Therapy - MSSA (Single Agent IV Antibiotic Therapy - MSSA) — West Virginia University. Single-agent intravenous antibiotic therapy targets and kills methicillin-susceptible Staphylococcus aureus (MSSA) by inhibiting bacterial cell wall synthesis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Single Agent IV Antibiotic Therapy - MSSA TARGET | Single Agent IV Antibiotic Therapy - MSSA | West Virginia University | marketed | Beta-lactam antibiotic | Penicillin-binding proteins (PBPs); bacterial cell wall peptidoglycan | |
| Amoxil | amoxicillin | Generic (originally Beecham/GSK) | marketed | Aminopenicillin (Beta-lactam antibiotic) | 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C | 1972-01-01 |
| Bicillin C-R | Penicillin G Benzathine | Pfizer | marketed | Beta-lactam antibiotic | Cell-wall peptidoglycan biosynthesis | 1952-01-01 |
| Bicillin C-R | Penicillin G Benzathine | Pfizer | marketed | Beta-lactam antibiotic | Cell-wall peptidoglycan biosynthesis | 1952-01-01 |
| Quick response: Amoxicillin for 3 days | Quick response: Amoxicillin for 3 days | University Hospital, Montpellier | marketed | Beta-lactam antibiotic (aminopenicillin) | Penicillin-binding proteins (PBPs) | |
| Rabeprazloe+bismuth+amoxicillin+clarithromycin | Rabeprazloe+bismuth+amoxicillin+clarithromycin | Xijing Hospital of Digestive Diseases | marketed | Proton pump inhibitor + bismuth salt + beta-lactam antibiotic + macrolide antibiotic combination | H+ ATPase (rabeprazole); H. pylori urease and cell wall (bismuth); bacterial peptidoglycan (amoxicillin); bacterial ribosome (clarithromycin) | |
| Fosfomycin and imipenem | Fosfomycin and imipenem | Juan A. Arnaiz | marketed | Beta-lactam antibiotic combination | Bacterial cell wall synthesis (MurA enzyme and penicillin-binding proteins) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Amoxil · 8778924 · Compound · US
- — Amoxil · 8357394 · Formulation · US
- — Amoxil · 8299052 · Method of Use · US
Sponsor landscape (Beta-lactam antibiotic class)
- Pfizer · 2 drugs in this class
- Bayer · 1 drug in this class
- Belén Retamal-Valdes · 1 drug in this class
- Benova (Tianjin) Innovative medicine Research Co., Ltd. · 1 drug in this class
- Esraa Salah Mohamed Abdallah Eladl · 1 drug in this class
- Incheon St.Mary's Hospital · 1 drug in this class
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group · 1 drug in this class
- KEMRI-Wellcome Trust Collaborative Research Program · 1 drug in this class
- National Taiwan University Hospital · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Single Agent IV Antibiotic Therapy - MSSA — Competitive Intelligence Brief. https://druglandscape.com/ci/single-agent-iv-antibiotic-therapy-mssa. Accessed 2026-05-16.
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