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Simbrinza 0.2%-1% Ophthalmic Suspension — Competitive Intelligence Brief
marketed
Fixed-dose combination of carbonic anhydrase inhibitor and alpha-2 adrenergic agonist
Carbonic anhydrase II; alpha-2 adrenergic receptor
Ophthalmology
Small molecule
Live · refreshed every 30 min
Target snapshot
Simbrinza 0.2%-1% Ophthalmic Suspension (Simbrinza 0.2%-1% Ophthalmic Suspension) — Prairie Eye Center. Simbrinza combines a beta-adrenergic antagonist and a carbonic anhydrase inhibitor to reduce intraocular pressure by decreasing aqueous humor production.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Simbrinza 0.2%-1% Ophthalmic Suspension TARGET | Simbrinza 0.2%-1% Ophthalmic Suspension | Prairie Eye Center | marketed | Fixed-dose combination of carbonic anhydrase inhibitor and alpha-2 adrenergic agonist | Carbonic anhydrase II; alpha-2 adrenergic receptor | |
| Brinzolamide/Brimonidine FC | Brinzolamide/Brimonidine FC | University Hospital of Patras | marketed | Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination | Carbonic anhydrase II; Alpha-2 adrenergic receptor | |
| Brinzolamide/brimonidine ophthalmic suspension | Brinzolamide/brimonidine ophthalmic suspension | Padagis LLC | phase 3 | Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination | Carbonic anhydrase II; Alpha-2 adrenergic receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Fixed-dose combination of carbonic anhydrase inhibitor and alpha-2 adrenergic agonist class)
- Prairie Eye Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Simbrinza 0.2%-1% Ophthalmic Suspension — Competitive Intelligence Brief. https://druglandscape.com/ci/simbrinza-0-2-1-ophthalmic-suspension. Accessed 2026-05-17.
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