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SHR-A1904 — Competitive Intelligence Brief
phase 3
Bispecific antibody; PD-1/TGF-β inhibitor
PD-1 and TGF-β
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
SHR-A1904 (SHR-A1904) — Shanghai Hengrui Pharmaceutical Co., Ltd.. SHR-A1904 is a bispecific antibody that simultaneously engages PD-1 on immune cells and TGF-β in the tumor microenvironment to enhance anti-tumor immunity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SHR-A1904 TARGET | SHR-A1904 | Shanghai Hengrui Pharmaceutical Co., Ltd. | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| IBI362 | IBI362 | Innovent Biologics (Suzhou) Co. Ltd. | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| BAT1706 | BAT1706 | Bio-Thera Solutions | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| BAT1406 | BAT1406 | Bio-Thera Solutions | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| IBI354 | IBI354 | Innovent Biologics (Suzhou) Co. Ltd. | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| IBI343 | IBI343 | Innovent Biologics (Suzhou) Co. Ltd. | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| SHR-1918 Injection | SHR-1918 Injection | Beijing Suncadia Pharmaceuticals Co., Ltd | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific antibody; PD-1/TGF-β inhibitor class)
- Bio-Thera Solutions · 3 drugs in this class
- Innovent Biologics (Suzhou) Co. Ltd. · 3 drugs in this class
- Beijing Suncadia Pharmaceuticals Co., Ltd · 1 drug in this class
- Shanghai Hengrui Pharmaceutical Co., Ltd. · 1 drug in this class
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- SHR-A1904 CI watch — RSS
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- SHR-A1904 alone — RSS
- Whole Bispecific antibody; PD-1/TGF-β inhibitor class — RSS
Cite this brief
Drug Landscape (2026). SHR-A1904 — Competitive Intelligence Brief. https://druglandscape.com/ci/shr-a1904. Accessed 2026-05-13.
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