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SGLT2i+Metformin+Linagliptin — Competitive Intelligence Brief
marketed
Combination antidiabetic agent (SGLT2 inhibitor + biguanide + DPP-4 inhibitor)
SGLT2 transporter, mitochondrial complex I (metformin), dipeptidyl peptidase-4
Diabetes
Small molecule
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Target snapshot
SGLT2i+Metformin+Linagliptin (SGLT2i+Metformin+Linagliptin) — Huazhong University of Science and Technology. This triple-combination therapy reduces blood glucose through three complementary mechanisms: blocking renal glucose reabsorption (SGLT2i), enhancing insulin secretion and sensitivity (metformin), and inhibiting dipeptidyl peptidase-4 to prolong incretin action (linagliptin).
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SGLT2i+Metformin+Linagliptin TARGET | SGLT2i+Metformin+Linagliptin | Huazhong University of Science and Technology | marketed | Combination antidiabetic agent (SGLT2 inhibitor + biguanide + DPP-4 inhibitor) | SGLT2 transporter, mitochondrial complex I (metformin), dipeptidyl peptidase-4 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination antidiabetic agent (SGLT2 inhibitor + biguanide + DPP-4 inhibitor) class)
- Huazhong University of Science and Technology · 1 drug in this class
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Cite this brief
Drug Landscape (2026). SGLT2i+Metformin+Linagliptin — Competitive Intelligence Brief. https://druglandscape.com/ci/sglt2i-metformin-linagliptin. Accessed 2026-05-16.
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