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Sevoflurane (Preconditioning) — Competitive Intelligence Brief
marketed
Volatile anesthetic with cardioprotective preconditioning properties
Mitochondrial ATP-sensitive potassium channels (mitoKATP); protein kinase C; endothelial nitric oxide synthase
Cardiovascular; Perioperative Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
Sevoflurane (Preconditioning) (Sevoflurane (Preconditioning)) — University of Zurich. Sevoflurane, when used as a preconditioning agent, activates cellular protective pathways that reduce ischemia-reperfusion injury by triggering mitochondrial ATP-sensitive potassium channels and anti-apoptotic signaling.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Sevoflurane (Preconditioning) TARGET | Sevoflurane (Preconditioning) | University of Zurich | marketed | Volatile anesthetic with cardioprotective preconditioning properties | Mitochondrial ATP-sensitive potassium channels (mitoKATP); protein kinase C; endothelial nitric oxide synthase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Volatile anesthetic with cardioprotective preconditioning properties class)
- University of Zurich · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Sevoflurane (Preconditioning) — Competitive Intelligence Brief. https://druglandscape.com/ci/sevoflurane-preconditioning. Accessed 2026-05-15.
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