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Seroquel (quetiapine) — Competitive Intelligence Brief
marketed
Atypical antipsychotic
Dopamine D2 receptor, serotonin 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Seroquel (quetiapine) (Seroquel (quetiapine)) — AstraZeneca. Quetiapine blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and stabilize mood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Seroquel (quetiapine) TARGET | Seroquel (quetiapine) | AstraZeneca | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor | |
| quetiapine fumarate vs risperidone | quetiapine fumarate vs risperidone | AstraZeneca | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor | |
| Quetiapine Immediate Release | Quetiapine Immediate Release | AstraZeneca | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| placebo with Clozapine | placebo with Clozapine | Shanghai Mental Health Center | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Risperdal,reminyl | Risperdal,reminyl | Jinan Mental Hospital | marketed | Atypical antipsychotic (Risperdal); Cholinesterase inhibitor (Reminyl) | Dopamine D2 receptor, serotonin 5-HT2A receptor (Risperdal); Acetylcholinesterase (Reminyl) | |
| olanzapine + fluoxetine | olanzapine + fluoxetine | University of Florida | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| quetiapine (Seroquel) XR | quetiapine (Seroquel) XR | Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc. | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Seroquel (quetiapine) — Competitive Intelligence Brief. https://druglandscape.com/ci/seroquel-quetiapine. Accessed 2026-05-16.
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