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Seroquel and Risperidone — Competitive Intelligence Brief
marketed
Atypical antipsychotic
Dopamine D2 receptor, Serotonin 5-HT2A receptor
Psychiatry/Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Seroquel and Risperidone (Seroquel and Risperidone) — AstraZeneca. Both drugs are atypical antipsychotics that block dopamine D2 receptors and serotonin 5-HT2A receptors in the brain to reduce psychotic symptoms and stabilize mood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Seroquel and Risperidone TARGET | Seroquel and Risperidone | AstraZeneca | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| sodium valproate with Clozapine | sodium valproate with Clozapine | Shanghai Mental Health Center | marketed | Antipsychotic + mood stabilizer combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase | |
| Risperdal,reminyl | Risperdal,reminyl | Jinan Mental Hospital | marketed | Atypical antipsychotic (Risperdal); Cholinesterase inhibitor (Reminyl) | Dopamine D2 receptor, serotonin 5-HT2A receptor (Risperdal); Acetylcholinesterase (Reminyl) | |
| Quetiapine (drug) | Quetiapine (drug) | Medical University of Vienna | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Quetiapine or Risperidone + Aripiprazole | Quetiapine or Risperidone + Aripiprazole | Otsuka Pharmaceutical Development & Commercialization, Inc. | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor | |
| Lithium carbonate + perospirone hydrochloride | Lithium carbonate + perospirone hydrochloride | Shanghai Mental Health Center | marketed | Mood stabilizer + atypical antipsychotic combination | Inositol monophosphatase, GSK-3 (lithium); dopamine D2 receptor, serotonin 5-HT2A receptor (perospirone) | |
| Oral Olanzapine | Oral Olanzapine | Eli Lilly and Company | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Seroquel and Risperidone — Competitive Intelligence Brief. https://druglandscape.com/ci/seroquel-and-risperidone. Accessed 2026-05-13.
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