Who are Sefaxersen (RO7434656)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Hympavzi, Eliquis, Xarelto, Heparin Sodium In Plastic Container, Rivaroxaban, dabigatran, apixaban, or edoxaban, Low dose nadroparin.

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Last reviewed 2026-06-09 · How we verify

Sefaxersen (RO7434656) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sefaxersen (RO7434656) (Sefaxersen (RO7434656)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Factor Xa inhibitor. Area: Cardiovascular.

phase 3 Factor Xa inhibitor Factor Xa Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Sefaxersen (RO7434656) (Sefaxersen (RO7434656)) — Hoffmann-La Roche. Sefaxersen is a direct Factor Xa inhibitor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Sefaxersen (RO7434656) TARGET	Sefaxersen (RO7434656)	Hoffmann-La Roche	phase 3	Factor Xa inhibitor	Factor Xa
Hympavzi	MARSTACIMAB	Pfizer Inc	marketed	Monoclonal Antibody	Factor Xa	2025-01-01
Eliquis	apixaban	Bristol-Myers Squibb	marketed	Factor Xa inhibitor	Factor Xa (FXa)	2012-01-01
Xarelto	rivaroxaban	Johnson & Johnson	marketed	Direct Factor Xa Inhibitor	Factor Xa (FXa)	2011-01-01
Heparin Sodium In Plastic Container	Heparin Sodium	Fresenius Kabi	marketed	Anti-coagulant	Antithrombin III, Factor Xa, Factor IIa	1939-01-01
Rivaroxaban, dabigatran, apixaban, or edoxaban	Rivaroxaban, dabigatran, apixaban, or edoxaban	Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec	marketed	Direct oral anticoagulant (DOAC)	Factor Xa (rivaroxaban, apixaban, edoxaban) or Thrombin (dabigatran)
Low dose nadroparin	Low dose nadroparin	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	marketed	Low-molecular-weight heparin (LMWH)	Factor Xa, Thrombin (Factor IIa)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2034-02-17 — Xarelto · 9539218 · Method of Use · US
2034-08-17 — Xarelto · 9539218*PED · Compound · US

Sponsor landscape (Factor Xa inhibitor class)

GlaxoSmithKline · 4 drugs in this class
Bayer · 2 drugs in this class
China National Center for Cardiovascular Diseases · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Kim, Seok Jin · 1 drug in this class
NYU Langone Health · 1 drug in this class
Paul Di Cesare,MD · 1 drug in this class
Pfizer · 1 drug in this class
Queen Mary University of London · 1 drug in this class
Queen's University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sefaxersen (RO7434656) — Competitive Intelligence Brief. https://druglandscape.com/ci/sefaxersen-ro7434656. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing