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Lybalvi — Competitive Intelligence Brief

Lybalvi (SAMIDORPHAN) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Atypical Antipsychotic [EPC]. Area: Neuroscience.

marketed Atypical Antipsychotic [EPC] Mu-type opioid receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Lybalvi (SAMIDORPHAN) — Alkermes Inc. Lybalvi blocks the action of opioids at their receptor sites in the brain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Lybalvi TARGET SAMIDORPHAN Alkermes Inc marketed Atypical Antipsychotic [EPC] Mu-type opioid receptor 2021-01-01
Olinvyk OLICERIDINE Trevena marketed Mu-type opioid receptor 2020-01-01
Symproic NALDEMEDINE Bdsi marketed Opioid Antagonist Mu-type opioid receptor 2017-01-01
Viberzi ELUXADOLINE AbbVie marketed mu-Opioid Receptor Agonist [EPC] Mu-type opioid receptor 2015-01-01
Movantik NALOXEGOL Averitas marketed Opioid Antagonist Mu-type opioid receptor 2014-01-01
Relistor METHYLNALTREXONE Salix Pharms marketed Opioid Antagonist Mu-type opioid receptor 2008-01-01
Nucynta TAPENTADOL Collegium Pharm Inc marketed Opioid Agonist Mu-type opioid receptor 2008-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Atypical Antipsychotic [EPC] class)

  1. · 2 drugs in this class
  2. AbbVie · 1 drug in this class
  3. Alkermes Inc · 1 drug in this class
  4. Eli Lilly · 1 drug in this class
  5. Hisamitsu · 1 drug in this class
  6. Intra-Cellular · 1 drug in this class
  7. Jazz Pharmaceuticals · 1 drug in this class
  8. Johnson & Johnson (Janssen) · 1 drug in this class
  9. Otsuka · 1 drug in this class
  10. Vanda Pharms Inc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Lybalvi — Competitive Intelligence Brief. https://druglandscape.com/ci/samidorphan. Accessed 2026-05-14.

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