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S-1 + Cisplatin (arm A) — Competitive Intelligence Brief

S-1 + Cisplatin (arm A) (S-1 + Cisplatin (arm A)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Fluoropyrimidine + platinum-based chemotherapy combination. Area: Oncology.

phase 3 Fluoropyrimidine + platinum-based chemotherapy combination Thymidylate synthase (S-1); DNA (cisplatin) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

S-1 + Cisplatin (arm A) (S-1 + Cisplatin (arm A)) — Taiho Pharmaceutical Co., Ltd.. S-1 is an oral fluoropyrimidine prodrug that inhibits thymidylate synthase and other enzymes in nucleotide synthesis, while cisplatin is a platinum-based alkylating agent that cross-links DNA, together producing synergistic cytotoxic effects against cancer cells.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
S-1 + Cisplatin (arm A) TARGET S-1 + Cisplatin (arm A) Taiho Pharmaceutical Co., Ltd. phase 3 Fluoropyrimidine + platinum-based chemotherapy combination Thymidylate synthase (S-1); DNA (cisplatin)
S-1 & Oxaliplatin S-1 & Oxaliplatin The First Affiliated Hospital with Nanjing Medical University phase 3 Fluoropyrimidine + platinum-based chemotherapy combination Thymidylate synthase (S-1); DNA (oxaliplatin)
TS-1, oxaliplatin TS-1, oxaliplatin Samsung Medical Center phase 3 Fluoropyrimidine + platinum-based chemotherapy combination Thymidylate synthase; DNA (platinum crosslinking)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Fluoropyrimidine + platinum-based chemotherapy combination class)

  1. Samsung Medical Center · 1 drug in this class
  2. Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
  3. The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). S-1 + Cisplatin (arm A) — Competitive Intelligence Brief. https://druglandscape.com/ci/s-1-cisplatin-arm-a. Accessed 2026-05-16.

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