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S-1 and cisplatin — Competitive Intelligence Brief
phase 3
Fluoropyrimidine antimetabolite + platinum-based alkylating agent
Thymidylate synthase (S-1); DNA (cisplatin)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
S-1 and cisplatin (S-1 and cisplatin) — Asan Medical Center. S-1 is a combination of three components that inhibit thymidylate synthase and other enzymes in the pyrimidine synthesis pathway, while cisplatin is a platinum-based alkylating agent that cross-links DNA, together producing synergistic cytotoxic effects against cancer cells.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| S-1 and cisplatin TARGET | S-1 and cisplatin | Asan Medical Center | phase 3 | Fluoropyrimidine antimetabolite + platinum-based alkylating agent | Thymidylate synthase (S-1); DNA (cisplatin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Fluoropyrimidine antimetabolite + platinum-based alkylating agent class)
- Asan Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). S-1 and cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/s-1-and-cisplatin. Accessed 2026-05-16.
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