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RSD1235 — Competitive Intelligence Brief
phase 3
Potassium channel opener
ATP-sensitive potassium channels (KATP)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
RSD1235 (RSD1235) — Astellas Pharma Inc. RSD1235 is a potassium channel opener that suppresses atrial fibrillation by prolonging atrial refractoriness and reducing atrial conduction velocity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| RSD1235 TARGET | RSD1235 | Astellas Pharma Inc | phase 3 | Potassium channel opener | ATP-sensitive potassium channels (KATP) | |
| Rogaine | minoxidil | Generic (originally Upjohn/Pfizer) | marketed | Vasodilator (potassium channel opener), Hair growth stimulant | ATP-sensitive inward rectifier potassium channel 1, Sulfonylurea receptor 2, Kir6.2 | 1988-08-18 |
| Minoxidil 5 % Topical Spray | Minoxidil 5 % Topical Spray | Sheikh Zayed Federal Postgraduate Medical Institute | marketed | Potassium channel opener / Topical hair growth stimulant | ATP-sensitive potassium channels (KATP) | |
| KAD-1229 | KAD-1229 | Kissei Pharmaceutical Co., Ltd. | marketed | Potassium channel opener | ATP-sensitive potassium channel (KATP) | |
| Ezogabine/Retigabine IR | Ezogabine/Retigabine IR | GlaxoSmithKline | marketed | Potassium channel opener | Kv7 (KCNQ) voltage-gated potassium channels | |
| minoxidil 5% solution | minoxidil 5% solution | Allergan | marketed | Potassium channel opener | ATP-sensitive potassium channels | |
| ezogabine/retigabine | ezogabine/retigabine | GlaxoSmithKline | marketed | Potassium channel opener; anticonvulsant | KCNQ potassium channels (Kv7) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium channel opener class)
- Kissei Pharmaceutical Co., Ltd. · 2 drugs in this class
- Astellas Pharma Inc · 1 drug in this class
- Cardurion Pharmaceuticals, Inc. · 1 drug in this class
- Dr. dr. Lili Legiawati, SpKK(K) · 1 drug in this class
- Eurofarma Laboratorios S.A. · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Allergan · 1 drug in this class
- Triple Hair Inc · 1 drug in this class
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Cite this brief
Drug Landscape (2026). RSD1235 — Competitive Intelligence Brief. https://druglandscape.com/ci/rsd1235. Accessed 2026-05-13.
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