Who are RPV + DRV/r's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): ZDV+3TC+LPV/r, AZT+3TC+IDV+RTV, Combivir+Reyataz.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

RPV + DRV/r — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RPV + DRV/r (RPV + DRV/r) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiretroviral combination (NNRTI + protease inhibitor). Area: Infectious Disease / Virology.

phase 3 Antiretroviral combination (NNRTI + protease inhibitor) HIV reverse transcriptase; HIV protease Infectious Disease / Virology Small molecule Live · refreshed every 30 min

Target snapshot

RPV + DRV/r (RPV + DRV/r) — ASST Fatebenefratelli Sacco. RPV (rilpivirine) and DRV/r (darunavir/ritonavir) are antiretroviral agents that inhibit HIV reverse transcriptase and protease, respectively, blocking viral replication.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
RPV + DRV/r TARGET	RPV + DRV/r	ASST Fatebenefratelli Sacco	phase 3	Antiretroviral combination (NNRTI + protease inhibitor)	HIV reverse transcriptase; HIV protease
ZDV+3TC+LPV/r	ZDV+3TC+LPV/r	International Maternal Pediatric Adolescent AIDS Clinical Trials Group	marketed	Antiretroviral combination therapy (NRTI + PI)	HIV reverse transcriptase; HIV protease
AZT+3TC+IDV+RTV	AZT+3TC+IDV+RTV	Hospital Clinic of Barcelona	marketed	Antiretroviral combination therapy (NRTI + PI)	HIV reverse transcriptase; HIV protease
Combivir+Reyataz	Combivir+Reyataz	Hospital Clinic of Barcelona	marketed	Antiretroviral combination therapy (NRTI + protease inhibitor)	HIV reverse transcriptase; HIV protease

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiretroviral combination (NNRTI + protease inhibitor) class)

ASST Fatebenefratelli Sacco · 1 drug in this class

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Cite this brief

Drug Landscape (2026). RPV + DRV/r — Competitive Intelligence Brief. https://druglandscape.com/ci/rpv-drv-r. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing