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RO0503821 (1x/4 Weeks) — Competitive Intelligence Brief
phase 3
S1P receptor modulator
S1P1
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
RO0503821 (1x/4 Weeks) (RO0503821 (1x/4 Weeks)) — Hoffmann-La Roche. RO0503821 is a small molecule that targets the S1P1 receptor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| RO0503821 (1x/4 Weeks) TARGET | RO0503821 (1x/4 Weeks) | Hoffmann-La Roche | phase 3 | S1P receptor modulator | S1P1 | |
| fingolimob (FTY) | fingolimob (FTY) | University Hospital, Clermont-Ferrand | marketed | Sphingosine-1-phosphate receptor modulator | S1P1 receptor (sphingosine-1-phosphate receptor 1) | |
| FTY720 | FTY720 | Novartis Pharmaceuticals | marketed | Sphingosine-1-phosphate receptor modulator; Immunomodulator | Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5) | |
| Group S+T | Group S+T | Huazhong University of Science and Technology | marketed | S1P receptor modulator | S1P1 | |
| Centhaquine + Standard Treatment | Centhaquine + Standard Treatment | Pharmazz, Inc. | phase 3 | S1P receptor agonist | Sphingosine-1-phosphate receptor 1 (S1P1) | |
| Placebo matching fingolimod | Placebo matching fingolimod | Biogen | phase 3 | Sphingosine-1-phosphate receptor modulator | S1P1, S1P3, S1P4, S1P5 (sphingosine-1-phosphate receptors) | |
| RPC1063 | RPC1063 | Celgene | phase 3 | S1P receptor modulator | S1P1 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (S1P receptor modulator class)
- Promius Pharma, LLC · 2 drugs in this class
- Nobelpharma · 2 drugs in this class
- Bausch & Lomb Incorporated · 1 drug in this class
- Biogen · 1 drug in this class
- Celgene · 1 drug in this class
- Geropharm · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- Huazhong University of Science and Technology · 1 drug in this class
- Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). RO0503821 (1x/4 Weeks) — Competitive Intelligence Brief. https://druglandscape.com/ci/ro0503821-1x-4-weeks. Accessed 2026-05-16.
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