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RO0503821 (1x/4 Weeks) — Competitive Intelligence Brief

RO0503821 (1x/4 Weeks) (RO0503821 (1x/4 Weeks)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: S1P receptor modulator. Area: Immunology.

phase 3 S1P receptor modulator S1P1 Immunology Small molecule Live · refreshed every 30 min

Target snapshot

RO0503821 (1x/4 Weeks) (RO0503821 (1x/4 Weeks)) — Hoffmann-La Roche. RO0503821 is a small molecule that targets the S1P1 receptor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
RO0503821 (1x/4 Weeks) TARGET RO0503821 (1x/4 Weeks) Hoffmann-La Roche phase 3 S1P receptor modulator S1P1
fingolimob (FTY) fingolimob (FTY) University Hospital, Clermont-Ferrand marketed Sphingosine-1-phosphate receptor modulator S1P1 receptor (sphingosine-1-phosphate receptor 1)
FTY720 FTY720 Novartis Pharmaceuticals marketed Sphingosine-1-phosphate receptor modulator; Immunomodulator Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5)
Group S+T Group S+T Huazhong University of Science and Technology marketed S1P receptor modulator S1P1
Centhaquine + Standard Treatment Centhaquine + Standard Treatment Pharmazz, Inc. phase 3 S1P receptor agonist Sphingosine-1-phosphate receptor 1 (S1P1)
Placebo matching fingolimod Placebo matching fingolimod Biogen phase 3 Sphingosine-1-phosphate receptor modulator S1P1, S1P3, S1P4, S1P5 (sphingosine-1-phosphate receptors)
RPC1063 RPC1063 Celgene phase 3 S1P receptor modulator S1P1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (S1P receptor modulator class)

  1. Promius Pharma, LLC · 2 drugs in this class
  2. Nobelpharma · 2 drugs in this class
  3. Bausch & Lomb Incorporated · 1 drug in this class
  4. Biogen · 1 drug in this class
  5. Celgene · 1 drug in this class
  6. Geropharm · 1 drug in this class
  7. GlaxoSmithKline · 1 drug in this class
  8. Hoffmann-La Roche · 1 drug in this class
  9. Huazhong University of Science and Technology · 1 drug in this class
  10. Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). RO0503821 (1x/4 Weeks) — Competitive Intelligence Brief. https://druglandscape.com/ci/ro0503821-1x-4-weeks. Accessed 2026-05-16.

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