Who are RO0503821 (1x/2 Weeks)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Elrexfio, Elrexfio, Elrantamab, DB-1303/BNT323, SHR-A1904, GR1803.

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Last reviewed 2026-06-09 · How we verify

RO0503821 (1x/2 Weeks) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RO0503821 (1x/2 Weeks) (RO0503821 (1x/2 Weeks)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific antibody. Area: Oncology.

phase 3 Bispecific antibody Oncology Small molecule Live · refreshed every 30 min

Target snapshot

RO0503821 (1x/2 Weeks) (RO0503821 (1x/2 Weeks)) — Hoffmann-La Roche. RO0503821 is a bispecific antibody that simultaneously engages two distinct molecular targets to enhance immune activation and tumor cell killing.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
RO0503821 (1x/2 Weeks) TARGET	RO0503821 (1x/2 Weeks)	Hoffmann-La Roche	phase 3	Bispecific antibody
Elrexfio	Elranatamab	Pfizer	marketed	Bispecific antibody	BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells	2023-01-01
Elrexfio	elranatamab	Pfizer	marketed	Bispecific antibody	BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells	2023-01-01
Elrantamab	elrantamab	Pfizer	marketed	Bispecific Antibody	BCMA (B-cell maturation antigen)
DB-1303/BNT323	DB-1303/BNT323	DualityBio Inc.	phase 3	Bispecific antibody
SHR-A1904	SHR-A1904	Shanghai Hengrui Pharmaceutical Co., Ltd.	phase 3	Bispecific antibody; PD-1/TGF-β inhibitor	PD-1 and TGF-β
GR1803	GR1803	Genrix (Shanghai) Biopharmaceutical Co., Ltd.	phase 3	Bispecific antibody

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

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Cite this brief

Drug Landscape (2026). RO0503821 (1x/2 Weeks) — Competitive Intelligence Brief. https://druglandscape.com/ci/ro0503821-1x-2-weeks. Accessed 2026-06-09.

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