Who are RNF's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): TBI-1301, TAK-667, MB-102 DMID, [68Ga]Ga-PentixaFor, Treatment Choice (TC), SHR-1314.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/rnf.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-13 · How we verify

RNF — Competitive Intelligence Brief

RNF (RNF) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CD47/SIRPα inhibitor. Area: Oncology.

phase 3 CD47/SIRPα inhibitor CD47 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

RNF (RNF) — Merck KGaA, Darmstadt, Germany. RNF is a small molecule targeting the CD47/SIRPα axis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
RNF TARGET	RNF	Merck KGaA, Darmstadt, Germany	phase 3	CD47/SIRPα inhibitor	CD47
TBI-1301	TBI-1301	Takara Bio Inc.	phase 3	CD47 antibody	CD47
TAK-667	TAK-667	Takeda	phase 3	CD47 antibody	CD47
MB-102 DMID	MB-102 DMID	Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.	phase 3	monoclonal antibody	CD47
[68Ga]Ga-PentixaFor	[68Ga]Ga-PentixaFor	Nantes University Hospital	phase 3	Radiopharmaceutical	CD47
Treatment Choice (TC)	Treatment Choice (TC)	Astex Pharmaceuticals, Inc.	phase 3	SIRPα inhibitor	CD47
SHR-1314	SHR-1314	Jiangsu HengRui Medicine Co., Ltd.	phase 3	CD47/SIRPα inhibitor	CD47/SIRPα axis

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CD47/SIRPα inhibitor class)

BicycleTx Limited · 1 drug in this class
Gustave Roussy, Cancer Campus, Grand Paris · 1 drug in this class
Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
Kuhnil Pharmaceutical Co., Ltd. · 1 drug in this class
Merck KGaA, Darmstadt, Germany · 1 drug in this class
Pharmicell Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). RNF — Competitive Intelligence Brief. https://druglandscape.com/ci/rnf. Accessed 2026-05-13.

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