Last reviewed · How we verify
RMC-6236 — Competitive Intelligence Brief
phase 3
KRAS G12C inhibitor
KRAS G12C
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
RMC-6236 (RMC-6236) — Revolution Medicines, Inc.. RMC-6236 is a selective inhibitor of KRAS G12C mutations that blocks oncogenic signaling in cancer cells.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| RMC-6236 TARGET | RMC-6236 | Revolution Medicines, Inc. | phase 3 | KRAS G12C inhibitor | KRAS G12C | |
| AMG 510 | AMG 510 | Criterium, Inc. | phase 3 | KRAS G12C inhibitor | KRAS G12C | |
| MRTX849 | MRTX849 | Mirati Therapeutics Inc. | phase 3 | KRAS G12C inhibitor | KRAS G12C |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (KRAS G12C inhibitor class)
- Criterium, Inc. · 1 drug in this class
- Dark Canyon Laboratories, LLC · 1 drug in this class
- Mirati Therapeutics Inc. · 1 drug in this class
- Revolution Medicines, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). RMC-6236 — Competitive Intelligence Brief. https://druglandscape.com/ci/rmc-6236. Accessed 2026-06-10.
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