Who are Risedronate Sodium (Actonel)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Boniva, Skelid, Aredia, Didronel, Risedronate (HMR4003), Zolendronic Acid.

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Last reviewed 2026-05-16 · How we verify

Risedronate Sodium (Actonel) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Risedronate Sodium (Actonel) (Risedronate Sodium (Actonel)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bisphosphonate. Area: Bone metabolism / Osteoporosis.

marketed Bisphosphonate Farnesyl pyrophosphate synthase (indirect); hydroxyapatite binding Bone metabolism / Osteoporosis Small molecule Live · refreshed every 30 min

Target snapshot

Risedronate Sodium (Actonel) (Risedronate Sodium (Actonel)) — Sanofi. Risedronate is a bisphosphonate that inhibits osteoclast-mediated bone resorption by binding to hydroxyapatite on the bone surface and blocking farnesyl pyrophosphate synthase in the mevalonate pathway.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Risedronate Sodium (Actonel) TARGET	Risedronate Sodium (Actonel)	Sanofi	marketed	Bisphosphonate	Farnesyl pyrophosphate synthase (indirect); hydroxyapatite binding
Boniva	IBANDRONIC ACID	Hoffmann La Roche	marketed	Bisphosphonate	Farnesyl pyrophosphate synthase	2003-01-01
Skelid	TILUDRONIC ACID		marketed	Bisphosphonate	72 kDa type IV collagenase	1997-01-01
Aredia	PAMIDRONIC ACID		marketed	Bisphosphonate	Farnesyl pyrophosphate synthase	1991-01-01
Didronel	ETIDRONIC ACID	Procter And Gamble	marketed	Bisphosphonate		1977-01-01
Risedronate (HMR4003)	Risedronate (HMR4003)	Sanofi	marketed	Bisphosphonate	Hydroxyapatite (bone mineral); osteoclast farnesyl pyrophosphate synthase
Zolendronic Acid	Zolendronic Acid	Wales Cancer Trials Unit	marketed	Bisphosphonate	Farnesyl pyrophosphate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bisphosphonate class)

· 2 drugs in this class
Amgen · 2 drugs in this class
National Taiwan University Hospital · 2 drugs in this class
Sanofi · 2 drugs in this class
Ludwig-Maximilians - University of Munich · 2 drugs in this class
Chinese University of Hong Kong · 1 drug in this class
Chinese Society of Lung Cancer · 1 drug in this class
Aarhus University Hospital · 1 drug in this class
Eisai Inc. · 1 drug in this class
Daiichi Sankyo Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Risedronate Sodium (Actonel) — Competitive Intelligence Brief. https://druglandscape.com/ci/risedronate-sodium-actonel. Accessed 2026-05-16.

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