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Risedronate (HMR4003) — Competitive Intelligence Brief
marketed
Bisphosphonate
Hydroxyapatite (bone mineral); osteoclast farnesyl pyrophosphate synthase
Bone metabolism / Rheumatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Risedronate (HMR4003) (Risedronate (HMR4003)) — Sanofi. Risedronate inhibits bone resorption by binding to hydroxyapatite on bone surfaces and inhibiting osteoclast activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Risedronate (HMR4003) TARGET | Risedronate (HMR4003) | Sanofi | marketed | Bisphosphonate | Hydroxyapatite (bone mineral); osteoclast farnesyl pyrophosphate synthase | |
| Boniva | IBANDRONIC ACID | Hoffmann La Roche | marketed | Bisphosphonate | Farnesyl pyrophosphate synthase | 2003-01-01 |
| Skelid | TILUDRONIC ACID | marketed | Bisphosphonate | 72 kDa type IV collagenase | 1997-01-01 | |
| Aredia | PAMIDRONIC ACID | marketed | Bisphosphonate | Farnesyl pyrophosphate synthase | 1991-01-01 | |
| Didronel | ETIDRONIC ACID | Procter And Gamble | marketed | Bisphosphonate | 1977-01-01 | |
| Hormone Replacement Therapy and Etidronate | Hormone Replacement Therapy and Etidronate | British Thoracic Society | marketed | Hormone replacement therapy combined with bisphosphonate | Estrogen receptor (HRT component); bone hydroxyapatite and osteoclast function (etidronate component) | |
| ibandronate [Bonviva/Boniva] | ibandronate [Bonviva/Boniva] | Hoffmann-La Roche | marketed | Bisphosphonate | Farnesyl pyrophosphate synthase (indirect); hydroxyapatite in bone (binding site) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bisphosphonate class)
- · 2 drugs in this class
- Amgen · 2 drugs in this class
- National Taiwan University Hospital · 2 drugs in this class
- Sanofi · 2 drugs in this class
- Ludwig-Maximilians - University of Munich · 2 drugs in this class
- Chinese University of Hong Kong · 1 drug in this class
- Chinese Society of Lung Cancer · 1 drug in this class
- Aarhus University Hospital · 1 drug in this class
- Eisai Inc. · 1 drug in this class
- Daiichi Sankyo Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Risedronate (HMR4003) — Competitive Intelligence Brief. https://druglandscape.com/ci/risedronate-hmr4003. Accessed 2026-05-16.
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