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rhPTH (1-84) — Competitive Intelligence Brief
marketed
PTH1 receptor agonist
PTH1 receptor
Endocrinology
Biologic
Live · refreshed every 30 min
Target snapshot
rhPTH (1-84) (rhPTH (1-84)) — Shire. rhPTH (1-84) is a recombinant human parathyroid hormone that binds to PTH1 receptors on bone cells to stimulate bone formation and increase serum calcium and phosphate levels.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| rhPTH (1-84) TARGET | rhPTH (1-84) | Shire | marketed | PTH1 receptor agonist | PTH1 receptor | |
| Teriparatide (Forteo) | Teriparatide (Forteo) | M.D. Anderson Cancer Center | marketed | Parathyroid hormone analog | PTH1 receptor (parathyroid hormone 1 receptor) | |
| Teriparatide Pen Injector | Teriparatide Pen Injector | University of Edinburgh | marketed | Parathyroid hormone analog | PTH1 receptor | |
| Teriparatide (rDNA origin) | Teriparatide (rDNA origin) | Bio Sidus SA | marketed | Parathyroid hormone analog | PTH1 receptor (PTHR1) | |
| Parathyroid Hormone (PTH) | Parathyroid Hormone (PTH) | Takeda | marketed | Peptide hormone / PTH1 receptor agonist | PTH1 receptor (PTHR1) | |
| teriparatide and raloxifene | teriparatide and raloxifene | Medical University of Vienna | marketed | Combination therapy: PTH analog and selective estrogen receptor modulator (SERM) | PTH1 receptor (teriparatide); estrogen receptor alpha and beta (raloxifene) | |
| teriparatide and alendronate | teriparatide and alendronate | Medical University of Vienna | marketed | Combination therapy: PTH analog + bisphosphonate | PTH1 receptor (teriparatide); farnesyl pyrophosphate synthase (alendronate) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PTH1 receptor agonist class)
- Shire · 1 drug in this class
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Cite this brief
Drug Landscape (2026). rhPTH (1-84) — Competitive Intelligence Brief. https://druglandscape.com/ci/rhpth-1-84. Accessed 2026-06-10.
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