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Rhenium-188-HEDP — Competitive Intelligence Brief
phase 3
Radiopharmaceutical
Bone hydroxyapatite (via HEDP bisphosphonate moiety)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Rhenium-188-HEDP (Rhenium-188-HEDP) — Amsterdam UMC, location VUmc. Rhenium-188-HEDP is a radiopharmaceutical that localizes to areas of increased bone metabolism and delivers beta radiation directly to bone lesions for pain palliation and potential therapeutic benefit.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rhenium-188-HEDP TARGET | Rhenium-188-HEDP | Amsterdam UMC, location VUmc | phase 3 | Radiopharmaceutical | Bone hydroxyapatite (via HEDP bisphosphonate moiety) | |
| Technetium Tc99m Sestamibi | Technetium Tc99m Sestamibi | Lantheus Medical Imaging | marketed | Radiopharmaceutical imaging agent | Mitochondrial membrane potential | |
| Copper Cu 64 Dotatate | Copper Cu 64 Dotatate | Vanderbilt-Ingram Cancer Center | marketed | Radiopharmaceutical; somatostatin receptor agonist imaging agent | Somatostatin receptor 2 (SSTR2) | |
| Sr-89 | Sr-89 | Peking Union Medical College Hospital | marketed | Radiopharmaceutical; beta-emitting radioisotope | Bone hydroxyapatite (calcium analog); osteoblasts in areas of increased bone metabolism | |
| Tc 99m filtered sulfur colloid | Tc 99m filtered sulfur colloid | Memorial Health University Medical Center | marketed | Radiopharmaceutical diagnostic agent | ||
| Tc-99m Pentetate | Tc-99m Pentetate | NYU Langone Health | marketed | Radiopharmaceutical diagnostic agent | ||
| Rubidium-82 | Rubidium-82 | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | marketed | PET radiopharmaceutical | Na+/K+-ATPase pump (myocardial uptake mechanism) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Radiopharmaceutical class)
- Amsterdam UMC, location VUmc · 1 drug in this class
- Blue Earth Diagnostics · 1 drug in this class
- Brigham and Women's Hospital · 1 drug in this class
- Genzyme, a Sanofi Company · 1 drug in this class
- Gustave Roussy, Cancer Campus, Grand Paris · 1 drug in this class
- HTA Co., Ltd. · 1 drug in this class
- IRCCS San Raffaele · 1 drug in this class
- ITEL Telecomunicazioni Srl · 1 drug in this class
- M.D. Anderson Cancer Center · 1 drug in this class
- Michael C Roarke, MD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rhenium-188-HEDP — Competitive Intelligence Brief. https://druglandscape.com/ci/rhenium-188-hedp. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing