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Retigabine IR — Competitive Intelligence Brief
phase 3
Potassium channel opener; anticonvulsant
Kv7 (KCNQ) voltage-gated potassium channels
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Retigabine IR (Retigabine IR) — GlaxoSmithKline. Retigabine opens voltage-gated potassium channels in neurons, increasing potassium efflux and reducing neuronal excitability.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Retigabine IR TARGET | Retigabine IR | GlaxoSmithKline | phase 3 | Potassium channel opener; anticonvulsant | Kv7 (KCNQ) voltage-gated potassium channels | |
| Rogaine | minoxidil | Generic (originally Upjohn/Pfizer) | marketed | Vasodilator (potassium channel opener), Hair growth stimulant | ATP-sensitive inward rectifier potassium channel 1, Sulfonylurea receptor 2, Kir6.2 | 1988-08-18 |
| Minoxidil 5 % Topical Spray | Minoxidil 5 % Topical Spray | Sheikh Zayed Federal Postgraduate Medical Institute | marketed | Potassium channel opener / Topical hair growth stimulant | ATP-sensitive potassium channels (KATP) | |
| Minoxidil Topical | Minoxidil Topical | Dr. dr. Lili Legiawati, SpKK(K) | marketed | Potassium channel opener | ATP-sensitive potassium channels | |
| Minoxidil 5% Topical Solution | Minoxidil 5% Topical Solution | Triple Hair Inc | marketed | Potassium channel opener | ATP-sensitive potassium channels (KATP) | |
| Minoxidil lotion 2% | Minoxidil lotion 2% | Mae Fah Luang University Hospital | marketed | Potassium channel opener / topical hair growth stimulant | ATP-sensitive potassium channels (KATP); exact follicle-specific target unclear | |
| ezogabine/retigabine | ezogabine/retigabine | GlaxoSmithKline | marketed | Potassium channel opener; anticonvulsant | KCNQ potassium channels (Kv7) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium channel opener; anticonvulsant class)
- GlaxoSmithKline · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Retigabine IR — Competitive Intelligence Brief. https://druglandscape.com/ci/retigabine-ir. Accessed 2026-05-14.
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