Who are REFRESH LIQUIGEL®'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Hyaluronic Acid and hydroxypropylmethylcellulose, Sodium Hyaluronate Ophthalmic 0.4%, methylcellulose 0.5%, TJO-018 (HA 0.15%), Retaine™, Preservative free artificial tear.

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Last reviewed 2026-05-13 · How we verify

REFRESH LIQUIGEL® — Competitive Intelligence Brief

REFRESH LIQUIGEL® (REFRESH LIQUIGEL®) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Artificial tear / ocular lubricant. Area: Ophthalmology.

marketed Artificial tear / ocular lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

REFRESH LIQUIGEL® (REFRESH LIQUIGEL®) — Allergan. REFRESH Liquigel provides ocular lubrication and protection by forming a viscous gel layer on the corneal surface to relieve dry eye symptoms.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
REFRESH LIQUIGEL® TARGET	REFRESH LIQUIGEL®	Allergan	marketed	Artificial tear / ocular lubricant
Hyaluronic Acid and hydroxypropylmethylcellulose	Hyaluronic Acid and hydroxypropylmethylcellulose	University of Sao Paulo	marketed	Artificial tear / ocular lubricant
Sodium Hyaluronate Ophthalmic 0.4%	Sodium Hyaluronate Ophthalmic 0.4%	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
methylcellulose 0.5%	methylcellulose 0.5%	Clinica Oftamologica Zona Sul	marketed	Artificial tear / Ocular lubricant
TJO-018 (HA 0.15%)	TJO-018 (HA 0.15%)	Taejoon Pharmaceutical Co., Ltd.	marketed	Artificial tear / Ocular lubricant	Ocular surface (non-receptor mediated)
Retaine™	Retaine™	Ocusoft, Inc.	marketed	Artificial tear / ocular lubricant
Preservative free artificial tear	Preservative free artificial tear	Fundação Altino Ventura	marketed	Artificial tear / Ocular lubricant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Artificial tear / ocular lubricant class)

Allergan · 2 drugs in this class
Chang Gung Memorial Hospital · 1 drug in this class
Guang'anmen Hospital of China Academy of Chinese Medical Sciences · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Nguyen Viet Giap · 1 drug in this class
ORA, Inc. · 1 drug in this class
Ocusoft, Inc. · 1 drug in this class
The Mentholatum Company · 1 drug in this class
Tianjin Eye Hospital · 1 drug in this class
University of Sao Paulo · 1 drug in this class

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Cite this brief

Drug Landscape (2026). REFRESH LIQUIGEL® — Competitive Intelligence Brief. https://druglandscape.com/ci/refresh-liquigel. Accessed 2026-05-13.

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