recombinant asparaginase — Competitive Intelligence Brief

recombinant asparaginase (recombinant asparaginase) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Enzyme. Area: Oncology.

marketed Enzyme Asparagine Oncology Small molecule

Target snapshot

recombinant asparaginase (recombinant asparaginase) — medac GmbH. Recombinant asparaginase depletes the amino acid asparagine from the bloodstream, starving asparagine-dependent leukemic cells of an essential nutrient required for protein synthesis.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
recombinant asparaginase TARGET	recombinant asparaginase	medac GmbH	marketed	Enzyme	Asparagine
Asparlas	calaspargase	Pfizer	marketed	Asparagine-specific Enzyme [EPC]	L-asparagine	2018-01-01
ASPARAGINASE ERWINIA CHRYSANTHEMI	ASPARAGINASE ERWINIA CHRYSANTHEMI		marketed	Asparagine-specific Enzyme [EPC]	L-asparagine	2011-01-01
Elspar	ASPARAGINASE	Merck & Co.	marketed	Asparagine-specific Enzyme [EPC]	L-asparagine	1994-01-01
Fe-ASP	Fe-ASP	Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.	marketed	Asparaginase conjugate	Asparagine synthetase (indirect target via asparagine depletion)
Erwinia asparaginase	Erwinia asparaginase	Andrew E. Place, MD	marketed	Enzyme	Asparagine
L-asparaginase	L-asparaginase	ERYtech Pharma	marketed	Enzyme (asparagine depleting agent)	Asparagine (substrate depletion mechanism)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Enzyme class)

1. Andrew E. Place, MD · 1 drug in this class
2. Dana-Farber Cancer Institute · 1 drug in this class
3. Medsearch · 1 drug in this class
4. medac GmbH · 1 drug in this class