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Rebif® new formulation (RNF) — Competitive Intelligence Brief

Rebif® new formulation (RNF) (Rebif® new formulation (RNF)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Interferon. Area: Immunology.

phase 3 Interferon IFNAR Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Rebif® new formulation (RNF) (Rebif® new formulation (RNF)) — EMD Serono Research & Development Institute, Inc.. Rebif new formulation (RNF) is an interferon beta-1a used to treat multiple sclerosis.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Rebif® new formulation (RNF) TARGET Rebif® new formulation (RNF) EMD Serono Research & Development Institute, Inc. phase 3 Interferon IFNAR
Peginterferon alfa-2b Injection Peginterferon alfa-2b Injection Nanfang Hospital, Southern Medical University marketed Interferon alfa Interferon-alpha receptor (IFNAR)
Pegyinterferon-alfa-2a Pegyinterferon-alfa-2a Chinese University of Hong Kong marketed Pegylated interferon Interferon-alfa receptor (IFNAR)
Peg-IFN + WB RBV for 24 weeks Peg-IFN + WB RBV for 24 weeks National Taiwan University Hospital marketed Immunomodulator + nucleoside analog antiviral combination Interferon-alpha receptor (IFNAR); HCV RNA-dependent RNA polymerase
Placebo and peginterferon Placebo and peginterferon National Taiwan University Hospital marketed Interferon alpha (pegylated) Interferon-alpha receptor (IFNAR)
INF1.0 + IBU INF1.0 + IBU St. Justine's Hospital marketed Interferon alfa + NSAID combination Interferon alfa receptor (IFNAR); COX-1 and COX-2
Pegylated IFN- alpha 2b Pegylated IFN- alpha 2b Ain Shams University marketed Interferon-alpha Interferon-alpha receptor (IFNAR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Interferon class)

  1. EMD Serono · 3 drugs in this class
  2. Cinnagen · 2 drugs in this class
  3. Tanabe Pharma Corporation · 2 drugs in this class
  4. Biogen · 1 drug in this class
  5. Celgene · 1 drug in this class
  6. EMD Serono Research & Development Institute, Inc. · 1 drug in this class
  7. Case Comprehensive Cancer Center · 1 drug in this class
  8. Hoffmann-La Roche · 1 drug in this class
  9. Human Genome Sciences Inc. · 1 drug in this class
  10. Bayer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Rebif® new formulation (RNF) — Competitive Intelligence Brief. https://druglandscape.com/ci/rebif-new-formulation-rnf. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing