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Rebif® (clone 484-39) — Competitive Intelligence Brief

Rebif® (clone 484-39) (Rebif® (clone 484-39)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Interferon beta-1a. Area: Immunology / Neurology.

marketed Interferon beta-1a Type I interferon receptor (IFNAR) Immunology / Neurology Biologic Live · refreshed every 30 min

Target snapshot

Rebif® (clone 484-39) (Rebif® (clone 484-39)) — Merck KGaA, Darmstadt, Germany. Rebif is an interferon beta-1a that activates interferon receptors on immune cells to modulate immune response and reduce inflammation in the central nervous system.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Rebif® (clone 484-39) TARGET Rebif® (clone 484-39) Merck KGaA, Darmstadt, Germany marketed Interferon beta-1a Type I interferon receptor (IFNAR)
Rebif New Formulation + ibuprofen PRN Rebif New Formulation + ibuprofen PRN Merck KGaA, Darmstadt, Germany phase 3 Interferon beta-1a Interferon-beta receptor (IFNAR)
Rebif New Formulation + prophylactic Ibuprofen Rebif New Formulation + prophylactic Ibuprofen Merck KGaA, Darmstadt, Germany phase 3 Interferon beta-1a Interferon-beta receptor (IFNBR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Interferon beta-1a class)

  1. Merck KGaA, Darmstadt, Germany · 3 drugs in this class

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Cite this brief

Drug Landscape (2026). Rebif® (clone 484-39) — Competitive Intelligence Brief. https://druglandscape.com/ci/rebif-clone-484-39. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing