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Rebamipide and Esomeprazole — Competitive Intelligence Brief

Rebamipide and Esomeprazole (Rebamipide and Esomeprazole) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Mucoprotective agent + Proton pump inhibitor combination. Area: Gastroenterology.

marketed Mucoprotective agent + Proton pump inhibitor combination Rebamipide: gastric mucosa protective mechanisms; Esomeprazole: H+/K+-ATPase Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Rebamipide and Esomeprazole (Rebamipide and Esomeprazole) — Otsuka Pharmaceutical, Inc., Philippines. This combination product uses rebamipide to protect and promote gastric mucosa healing while esomeprazole reduces gastric acid secretion to treat acid-related disorders.

Comparator set (1 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Rebamipide and Esomeprazole TARGET Rebamipide and Esomeprazole Otsuka Pharmaceutical, Inc., Philippines marketed Mucoprotective agent + Proton pump inhibitor combination Rebamipide: gastric mucosa protective mechanisms; Esomeprazole: H+/K+-ATPase
Rebamipide and Omeprazole Rebamipide and Omeprazole Otsuka Pakistan Limited phase 3 Mucoprotective agent + Proton pump inhibitor combination Rebamipide: gastric mucosa protective pathways; Omeprazole: H+/K+-ATPase (proton pump)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Mucoprotective agent + Proton pump inhibitor combination class)

  1. Otsuka Pakistan Limited · 1 drug in this class
  2. Otsuka Pharmaceutical, Inc., Philippines · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Rebamipide and Esomeprazole — Competitive Intelligence Brief. https://druglandscape.com/ci/rebamipide-and-esomeprazole. Accessed 2026-05-16.

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