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Rebamipide and Esomeprazole — Competitive Intelligence Brief
marketed
Mucoprotective agent + Proton pump inhibitor combination
Rebamipide: gastric mucosa protective mechanisms; Esomeprazole: H+/K+-ATPase
Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Rebamipide and Esomeprazole (Rebamipide and Esomeprazole) — Otsuka Pharmaceutical, Inc., Philippines. This combination product uses rebamipide to protect and promote gastric mucosa healing while esomeprazole reduces gastric acid secretion to treat acid-related disorders.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rebamipide and Esomeprazole TARGET | Rebamipide and Esomeprazole | Otsuka Pharmaceutical, Inc., Philippines | marketed | Mucoprotective agent + Proton pump inhibitor combination | Rebamipide: gastric mucosa protective mechanisms; Esomeprazole: H+/K+-ATPase | |
| Rebamipide and Omeprazole | Rebamipide and Omeprazole | Otsuka Pakistan Limited | phase 3 | Mucoprotective agent + Proton pump inhibitor combination | Rebamipide: gastric mucosa protective pathways; Omeprazole: H+/K+-ATPase (proton pump) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Mucoprotective agent + Proton pump inhibitor combination class)
- Otsuka Pakistan Limited · 1 drug in this class
- Otsuka Pharmaceutical, Inc., Philippines · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rebamipide and Esomeprazole — Competitive Intelligence Brief. https://druglandscape.com/ci/rebamipide-and-esomeprazole. Accessed 2026-05-16.
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