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Ramosetron, Aprepitant, Dexamethasone — Competitive Intelligence Brief
marketed
5-HT3 antagonist / NK1 antagonist / corticosteroid combination
5-HT3 receptor, NK1 receptor, glucocorticoid receptor
Oncology / Supportive Care
Small molecule
Live · refreshed every 30 min
Target snapshot
Ramosetron, Aprepitant, Dexamethasone (Ramosetron, Aprepitant, Dexamethasone) — Hallym University Medical Center. This is a fixed-dose combination of three antiemetic agents that work synergistically to prevent chemotherapy-induced nausea and vomiting (CINV) through different mechanisms: 5-HT3 antagonism, NK1 antagonism, and corticosteroid action.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ramosetron, Aprepitant, Dexamethasone TARGET | Ramosetron, Aprepitant, Dexamethasone | Hallym University Medical Center | marketed | 5-HT3 antagonist / NK1 antagonist / corticosteroid combination | 5-HT3 receptor, NK1 receptor, glucocorticoid receptor | |
| Ondansetron, dexamethasone, aprepitant | Ondansetron, dexamethasone, aprepitant | University of Oklahoma | phase 3 | Antiemetic combination (5-HT3 antagonist, NK1 antagonist, corticosteroid) | 5-HT3 receptor, NK1 receptor, glucocorticoid receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (5-HT3 antagonist / NK1 antagonist / corticosteroid combination class)
- Hallym University Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ramosetron, Aprepitant, Dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/ramosetron-aprepitant-dexamethasone. Accessed 2026-05-16.
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