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Raltegravir and truvada — Competitive Intelligence Brief
marketed
Antiretroviral combination (INSTI + NRTI)
HIV integrase; HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Raltegravir and truvada (Raltegravir and truvada) — The University of Texas Health Science Center, Houston. This combination uses raltegravir to block HIV integrase and truvada (emtricitabine/tenofovir) to inhibit reverse transcriptase, together suppressing HIV replication through dual antiretroviral action.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Raltegravir and truvada TARGET | Raltegravir and truvada | The University of Texas Health Science Center, Houston | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine | Dolutegravir/Lamivudine | Saint Michael's Medical Center | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Switch to DTG + 3TC | Switch to DTG + 3TC | Hospitales Universitarios Virgen del Rocío | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine as a single pill | Dolutegravir/Lamivudine as a single pill | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir / Lamivudine Pill | Dolutegravir / Lamivudine Pill | Charlotte-Paige Rolle, MD | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Raltegravir; Abacavir/Lamivudine | Raltegravir; Abacavir/Lamivudine | Central Institute of Epidemiology, Moscow, Russia | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside reverse transcriptase inhibitors) | HIV integrase; HIV reverse transcriptase | |
| Sofosbuvir, Ribavirin, and Stribild | Sofosbuvir, Ribavirin, and Stribild | Saint Michael's Medical Center | marketed | Direct-acting antiviral (DAA) combination; antiretroviral combination | HCV NS5B RNA polymerase; HIV integrase; HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination (INSTI + NRTI) class)
- ViiV Healthcare · 2 drugs in this class
- Denver Infectious Disease Consultants, PLLC · 1 drug in this class
- Fundacion SEIMC-GESIDA · 1 drug in this class
- Fundação Bahiana de Infectologia · 1 drug in this class
- Charlotte-Paige Rolle, MD · 1 drug in this class
- Saint Michael's Medical Center · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- Hospitales Universitarios Virgen del Rocío · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Raltegravir and truvada — Competitive Intelligence Brief. https://druglandscape.com/ci/raltegravir-and-truvada. Accessed 2026-05-16.
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