Last reviewed · How we verify
rAd-p53 gene — Competitive Intelligence Brief
marketed
Gene therapy; oncolytic virus
p53 tumor suppressor gene
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
rAd-p53 gene (rAd-p53 gene) — Shenzhen SiBiono GeneTech Co.,Ltd. rAd-p53 is a recombinant adenovirus carrying the wild-type p53 tumor suppressor gene that restores p53 function in cancer cells to induce apoptosis and inhibit tumor growth.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| rAd-p53 gene TARGET | rAd-p53 gene | Shenzhen SiBiono GeneTech Co.,Ltd | marketed | Gene therapy; oncolytic virus | p53 tumor suppressor gene | |
| chemotherapy plus p53 | chemotherapy plus p53 | Shenzhen SiBiono GeneTech Co.,Ltd | marketed | Combination chemotherapy with p53 gene therapy | p53 tumor suppressor protein | |
| Onasemnogene Abeparvovec-xioi | Onasemnogene Abeparvovec-xioi | Novartis Gene Therapies | marketed | Gene therapy | SMN1 gene | |
| p53 gene with surgery | p53 gene with surgery | Shenzhen SiBiono GeneTech Co.,Ltd | marketed | Gene therapy (p53 tumor suppressor) | p53 (tumor protein p53) | |
| Onasemnogene Abeparvovec-brve | Onasemnogene Abeparvovec-brve | Novartis Pharmaceuticals | marketed | Gene Therapy | SMN1 gene | |
| voretigene neparvovec-rzyl | voretigene neparvovec-rzyl | Spark Therapeutics, Inc. | marketed | Gene therapy | RPE65 gene | |
| p53 with chemotherapy | p53 with chemotherapy | Shenzhen SiBiono GeneTech Co.,Ltd | marketed | Gene therapy; recombinant adenovirus vector | p53 (tumor suppressor protein) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Gene therapy; oncolytic virus class)
- Shenzhen SiBiono GeneTech Co.,Ltd · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- rAd-p53 gene CI watch — RSS
- rAd-p53 gene CI watch — Atom
- rAd-p53 gene CI watch — JSON
- rAd-p53 gene alone — RSS
- Whole Gene therapy; oncolytic virus class — RSS
Cite this brief
Drug Landscape (2026). rAd-p53 gene — Competitive Intelligence Brief. https://druglandscape.com/ci/rad-p53-gene. Accessed 2026-06-10.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing