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rAd-p53 gene — Competitive Intelligence Brief

rAd-p53 gene (rAd-p53 gene) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Gene therapy; oncolytic virus. Area: Oncology.

marketed Gene therapy; oncolytic virus p53 tumor suppressor gene Oncology Small molecule Live · refreshed every 30 min

Target snapshot

rAd-p53 gene (rAd-p53 gene) — Shenzhen SiBiono GeneTech Co.,Ltd. rAd-p53 is a recombinant adenovirus carrying the wild-type p53 tumor suppressor gene that restores p53 function in cancer cells to induce apoptosis and inhibit tumor growth.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
rAd-p53 gene TARGET rAd-p53 gene Shenzhen SiBiono GeneTech Co.,Ltd marketed Gene therapy; oncolytic virus p53 tumor suppressor gene
chemotherapy plus p53 chemotherapy plus p53 Shenzhen SiBiono GeneTech Co.,Ltd marketed Combination chemotherapy with p53 gene therapy p53 tumor suppressor protein
Onasemnogene Abeparvovec-xioi Onasemnogene Abeparvovec-xioi Novartis Gene Therapies marketed Gene therapy SMN1 gene
p53 gene with surgery p53 gene with surgery Shenzhen SiBiono GeneTech Co.,Ltd marketed Gene therapy (p53 tumor suppressor) p53 (tumor protein p53)
Onasemnogene Abeparvovec-brve Onasemnogene Abeparvovec-brve Novartis Pharmaceuticals marketed Gene Therapy SMN1 gene
voretigene neparvovec-rzyl voretigene neparvovec-rzyl Spark Therapeutics, Inc. marketed Gene therapy RPE65 gene
p53 with chemotherapy p53 with chemotherapy Shenzhen SiBiono GeneTech Co.,Ltd marketed Gene therapy; recombinant adenovirus vector p53 (tumor suppressor protein)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Gene therapy; oncolytic virus class)

  1. Shenzhen SiBiono GeneTech Co.,Ltd · 1 drug in this class

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Cite this brief

Drug Landscape (2026). rAd-p53 gene — Competitive Intelligence Brief. https://druglandscape.com/ci/rad-p53-gene. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing