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Rabeprazole, metronidazole, Clarithromycin, Amoxicillin — Competitive Intelligence Brief

Rabeprazole, metronidazole, Clarithromycin, Amoxicillin (Rabeprazole, metronidazole, Clarithromycin, Amoxicillin) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Proton pump inhibitor + antibiotic combination therapy. Area: Gastroenterology / Infectious Disease.

marketed Proton pump inhibitor + antibiotic combination therapy H+ ATPase (rabeprazole); bacterial ribosome and DNA (metronidazole, clarithromycin); bacterial cell wall (amoxicillin) Gastroenterology / Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

Rabeprazole, metronidazole, Clarithromycin, Amoxicillin (Rabeprazole, metronidazole, Clarithromycin, Amoxicillin) — American University of Beirut Medical Center. This is a quadruple therapy combination that eradicates Helicobacter pylori by suppressing gastric acid and simultaneously attacking the bacteria with three antibiotics.

Comparator set (1 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Rabeprazole, metronidazole, Clarithromycin, Amoxicillin TARGET Rabeprazole, metronidazole, Clarithromycin, Amoxicillin American University of Beirut Medical Center marketed Proton pump inhibitor + antibiotic combination therapy H+ ATPase (rabeprazole); bacterial ribosome and DNA (metronidazole, clarithromycin); bacterial cell wall (amoxicillin)
Omeprazole, Amoxicillin, Metronidazole and Clarithromycin Omeprazole, Amoxicillin, Metronidazole and Clarithromycin Al-Azhar University marketed Proton pump inhibitor + antibiotic combination therapy H+ ATPase (omeprazole); bacterial ribosome and cell wall (amoxicillin, clarithromycin); bacterial DNA (metronidazole)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Proton pump inhibitor + antibiotic combination therapy class)

  1. Al-Azhar University · 1 drug in this class
  2. American University of Beirut Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Rabeprazole, metronidazole, Clarithromycin, Amoxicillin — Competitive Intelligence Brief. https://druglandscape.com/ci/rabeprazole-metronidazole-clarithromycin-amoxicillin. Accessed 2026-05-16.

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