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R2: Lenalidomide plus placebo maintenance — Competitive Intelligence Brief
phase 3
Immunomodulatory agent (IMiD)
Cereblon (CRBN)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
R2: Lenalidomide plus placebo maintenance (R2: Lenalidomide plus placebo maintenance) — University of Leeds. Lenalidomide is an immunomodulatory agent that enhances T-cell proliferation and NK cell activity while inhibiting TNF-α and IL-6 production, combined with placebo for maintenance therapy.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| R2: Lenalidomide plus placebo maintenance TARGET | R2: Lenalidomide plus placebo maintenance | University of Leeds | phase 3 | Immunomodulatory agent (IMiD) | Cereblon (CRBN) | |
| Lenalidomide PO (25mg) | Lenalidomide PO (25mg) | University Hospital, Lille | phase 3 | Immunomodulatory agent (IMiD) | Cereblon (CRBN) | |
| Lenalidomide (Control) | Lenalidomide (Control) | University of Chicago | phase 3 | Immunomodulatory agent (IMiD) | Cereblon (CRBN) | |
| Lenalidomide Oral Capsule | Lenalidomide Oral Capsule | The First Affiliated Hospital with Nanjing Medical University | phase 3 | Immunomodulatory agent (IMiD) | Cereblon (CRBN) | |
| CC-5013 (Revlimid™) | CC-5013 (Revlimid™) | University of Arkansas | phase 3 | Immunomodulatory agent (IMiD) | Cereblon (CRBN) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Immunomodulatory agent (IMiD) class)
- The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class
- University Hospital, Lille · 1 drug in this class
- University of Arkansas · 1 drug in this class
- University of Chicago · 1 drug in this class
- University of Leeds · 1 drug in this class
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Cite this brief
Drug Landscape (2026). R2: Lenalidomide plus placebo maintenance — Competitive Intelligence Brief. https://druglandscape.com/ci/r2-lenalidomide-plus-placebo-maintenance. Accessed 2026-05-16.
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