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R-CHOP/R-DHAP — Competitive Intelligence Brief

R-CHOP/R-DHAP (R-CHOP/R-DHAP) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Monoclonal antibody + chemotherapy combination. Area: Oncology.

phase 3 Monoclonal antibody + chemotherapy combination CD20 (rituximab component) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

R-CHOP/R-DHAP (R-CHOP/R-DHAP) — Prof. Dr. M. Dreyling (co-chairman). R-CHOP/R-DHAP is a combination chemotherapy regimen that uses rituximab (anti-CD20 monoclonal antibody) plus alternating cycles of CHOP and DHAP chemotherapy to kill lymphoma cells.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
R-CHOP/R-DHAP TARGET R-CHOP/R-DHAP Prof. Dr. M. Dreyling (co-chairman) phase 3 Monoclonal antibody + chemotherapy combination CD20 (rituximab component)
R-combination chemotherapy R-combination chemotherapy Shandong Provincial Hospital marketed Monoclonal antibody + chemotherapy combination CD20
Avastin®, paclitaxel, carboplatin Avastin®, paclitaxel, carboplatin Jiangsu HengRui Medicine Co., Ltd. phase 3 Anti-angiogenic monoclonal antibody + chemotherapy combination VEGF (bevacizumab); tubulin (paclitaxel); DNA (carboplatin)
BEVA+SOC BEVA+SOC Assistance Publique - Hôpitaux de Paris phase 3 Anti-angiogenic monoclonal antibody + chemotherapy combination VEGF (vascular endothelial growth factor)
Bevacizumab + FOLFIRI-3 Bevacizumab + FOLFIRI-3 AryoGen Pharmed Co. phase 3 Monoclonal antibody + chemotherapy combination VEGF (bevacizumab); Thymidylate synthase and topoisomerase I (FOLFIRI-3)
trastuzumab and chemotherapy trastuzumab and chemotherapy Comprehensive Support Project for Oncology Research phase 3 HER2-targeted monoclonal antibody + chemotherapy combination HER2 (human epidermal growth factor receptor 2)
Rituximab - CVP Rituximab - CVP The Lymphoma Academic Research Organisation phase 3 Monoclonal antibody + chemotherapy combination CD20

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Monoclonal antibody + chemotherapy combination class)

  1. Fujian Medical University · 2 drugs in this class
  2. Shandong Provincial Hospital · 2 drugs in this class
  3. The Lymphoma Academic Research Organisation · 2 drugs in this class
  4. Fondazione Italiana Linfomi - ETS · 2 drugs in this class
  5. Nordic Lymphoma Group · 1 drug in this class
  6. Prof. Dr. M. Dreyling (co-chairman) · 1 drug in this class
  7. American Scitech International · 1 drug in this class
  8. Universität des Saarlandes · 1 drug in this class
  9. AryoGen Pharmed Co. · 1 drug in this class
  10. Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). R-CHOP/R-DHAP — Competitive Intelligence Brief. https://druglandscape.com/ci/r-chop-r-dhap. Accessed 2026-05-16.

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