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R-CHOP; R-DA-EPOCH; R-HD MTX — Competitive Intelligence Brief
phase 3
Monoclonal antibody + chemotherapy combination
CD20 (rituximab component)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
R-CHOP; R-DA-EPOCH; R-HD MTX (R-CHOP; R-DA-EPOCH; R-HD MTX) — Shandong Provincial Hospital. R-CHOP, R-DA-EPOCH, and R-HD MTX are combination chemotherapy regimens that use rituximab (an anti-CD20 monoclonal antibody) combined with various cytotoxic chemotherapy agents to target and destroy B-cell lymphomas.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| R-CHOP; R-DA-EPOCH; R-HD MTX TARGET | R-CHOP; R-DA-EPOCH; R-HD MTX | Shandong Provincial Hospital | phase 3 | Monoclonal antibody + chemotherapy combination | CD20 (rituximab component) | |
| R-combination chemotherapy | R-combination chemotherapy | Shandong Provincial Hospital | marketed | Monoclonal antibody + chemotherapy combination | CD20 | |
| Trastuzumab+ chemotherapy | Trastuzumab+ chemotherapy | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | phase 3 | Monoclonal antibody + chemotherapy combination | HER2 (human epidermal growth factor receptor 2) | |
| R-CHOP/R-DHAP | R-CHOP/R-DHAP | Prof. Dr. M. Dreyling (co-chairman) | phase 3 | Monoclonal antibody + chemotherapy combination | CD20 (rituximab component) | |
| BEVA+SOC | BEVA+SOC | Assistance Publique - Hôpitaux de Paris | phase 3 | Anti-angiogenic monoclonal antibody + chemotherapy combination | VEGF (vascular endothelial growth factor) | |
| R-DA-EPOCH | R-DA-EPOCH | Fujian Medical University | phase 3 | Monoclonal antibody + chemotherapy combination | CD20 | |
| R-miniCHOP | R-miniCHOP | Universität des Saarlandes | phase 3 | Monoclonal antibody + chemotherapy combination | CD20 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody + chemotherapy combination class)
- Fujian Medical University · 2 drugs in this class
- Shandong Provincial Hospital · 2 drugs in this class
- The Lymphoma Academic Research Organisation · 2 drugs in this class
- Fondazione Italiana Linfomi - ETS · 2 drugs in this class
- Nordic Lymphoma Group · 1 drug in this class
- Prof. Dr. M. Dreyling (co-chairman) · 1 drug in this class
- American Scitech International · 1 drug in this class
- Universität des Saarlandes · 1 drug in this class
- AryoGen Pharmed Co. · 1 drug in this class
- Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). R-CHOP; R-DA-EPOCH; R-HD MTX — Competitive Intelligence Brief. https://druglandscape.com/ci/r-chop-r-da-epoch-r-hd-mtx. Accessed 2026-05-17.
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